| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 10 | 15 | 4.23 | .311 | 1.33 | 8.6 | 3.4 | 8.6 | 208.1 | 199 | 111 | 98 | 21 | 79 | 198 | 1 | 0 | 0 | 0 | 21 | 4 | 5 | 3.61 |
| SP | Gooden, D.Gooden, Dwight # >> | 21 | 1985 | R | 68 | 32 | 32 | 13 | 14 | 4.38 | .314 | 1.35 | 9.0 | 3.2 | 7.4 | 221.2 | 221 | 115 | 108 | 24 | 78 | 182 | 4 | 0 | 0 | 1 | 15 | 6 | 4 | 3.90 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 32 | 32 | 9 | 14 | 4.96 | .321 | 1.39 | 9.6 | 3.0 | 8.2 | 208.2 | 221 | 122 | 115 | 38 | 70 | 190 | 1 | 0 | 0 | 1 | 14 | 5 | 4 | 4.63 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 88 | 0 | 7 | 6 | 3.28 | .317 | 1.38 | 6.9 | 5.5 | 8.8 | 109.2 | 84 | 47 | 40 | 12 | 67 | 107 | 0 | 7 | 4 | 0 | 0 | 2 | 4 | 4.37 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 73 | 0 | 3 | 5 | 3.96 | .291 | 1.21 | 6.4 | 4.5 | 9.0 | 91.0 | 65 | 40 | 40 | 13 | 45 | 91 | 0 | 6 | 5 | 0 | 0 | 2 | 4 | 4.41 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 47 | 0 | 4 | 5 | 3.97 | .299 | 1.25 | 7.4 | 3.8 | 9.3 | 68.0 | 56 | 32 | 30 | 6 | 29 | 70 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.46 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 3 | 2 | 1 | 1 | 3.38 | .250 | 1.00 | 6.2 | 2.8 | 4.5 | 16.0 | 11 | 6 | 6 | 1 | 5 | 8 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 3.75 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 13 | 1 | 1 | 2 | 5.20 | .314 | 1.37 | 8.3 | 4.3 | 6.3 | 27.2 | 25 | 18 | 16 | 6 | 13 | 19 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 5.93 |