| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 26 | 26 | 14 | 6 | 3.39 | .291 | 1.22 | 9.2 | 1.8 | 7.1 | 172.2 | 176 | 72 | 65 | 20 | 35 | 135 | 5 | 0 | 0 | 2 | 15 | 2 | 5 | 3.59 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 26 | 26 | 7 | 12 | 5.76 | .326 | 1.44 | 9.9 | 3.2 | 6.2 | 148.1 | 162 | 98 | 95 | 25 | 52 | 102 | 4 | 0 | 0 | 1 | 8 | 1 | 2 | 4.89 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 83 | 24 | 24 | 6 | 8 | 6.17 | .328 | 1.45 | 10.4 | 2.6 | 8.2 | 127.0 | 147 | 87 | 87 | 28 | 37 | 116 | 1 | 0 | 0 | 0 | 8 | 2 | 2 | 4.96 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 24 | 23 | 9 | 8 | 4.42 | .326 | 1.43 | 9.7 | 3.2 | 5.5 | 150.2 | 162 | 76 | 74 | 22 | 54 | 92 | 5 | 0 | 0 | 1 | 13 | 3 | 2 | 4.82 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 25 | 23 | 4 | 9 | 6.83 | .363 | 1.70 | 12.3 | 3.1 | 4.9 | 114.2 | 156 | 91 | 87 | 26 | 39 | 62 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 5.93 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 68 | 0 | 5 | 3 | 3.49 | .324 | 1.41 | 8.1 | 4.6 | 8.4 | 80.0 | 72 | 38 | 31 | 5 | 41 | 75 | 0 | 28 | 3 | 0 | 0 | 2 | 4 | 3.55 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 67 | 0 | 1 | 1 | 3.75 | .303 | 1.30 | 7.7 | 4.1 | 8.9 | 74.1 | 63 | 32 | 31 | 12 | 34 | 73 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 4.51 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 70 | 0 | 5 | 7 | 5.04 | .324 | 1.44 | 9.7 | 3.2 | 7.1 | 75.0 | 81 | 46 | 42 | 14 | 27 | 59 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 4.93 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 56 | 0 | 3 | 5 | 4.09 | .317 | 1.36 | 8.3 | 4.0 | 12.3 | 66.0 | 61 | 30 | 30 | 8 | 29 | 90 | 0 | 1 | 3 | 0 | 0 | 2 | 2 | 3.26 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 70 | 0 | 6 | 3 | 3.93 | .304 | 1.30 | 9.1 | 2.5 | 8.4 | 71.0 | 72 | 36 | 31 | 10 | 20 | 66 | 0 | 2 | 0 | 0 | 0 | 1 | 8 | 3.86 |