| SP | Koufax, S.Koufax, Sandy † # >> | 30 | 1965 | L | 97 | 34 | 34 | 16 | 10 | 3.13 | .254 | 1.01 | 7.1 | 1.9 | 8.0 | 264.2 | 209 | 94 | 92 | 23 | 57 | 236 | 10 | 0 | 0 | 4 | 22 | 5 | 2 | 3.05 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 75 | 33 | 33 | 11 | 15 | 4.54 | .311 | 1.33 | 9.2 | 2.8 | 4.9 | 224.0 | 230 | 121 | 113 | 13 | 69 | 122 | 8 | 0 | 0 | 4 | 17 | 5 | 0 | 3.66 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 32 | 32 | 11 | 14 | 4.50 | .304 | 1.29 | 9.5 | 2.1 | 4.5 | 216.0 | 227 | 117 | 108 | 26 | 51 | 108 | 4 | 0 | 0 | 0 | 19 | 5 | 2 | 4.34 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 85 | 0 | 5 | 5 | 2.60 | .294 | 1.18 | 7.4 | 3.4 | 9.2 | 110.2 | 90 | 34 | 32 | 10 | 41 | 113 | 0 | 11 | 2 | 0 | 0 | 7 | 1 | 3.44 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 70 | 0 | 3 | 4 | 3.40 | .305 | 1.29 | 6.8 | 4.9 | 9.1 | 92.2 | 70 | 36 | 35 | 8 | 50 | 93 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 3.80 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 60 | 0 | 5 | 4 | 3.27 | .324 | 1.42 | 8.6 | 4.2 | 5.2 | 66.0 | 63 | 27 | 24 | 5 | 31 | 38 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 4.29 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 51 | 0 | 2 | 5 | 6.28 | .338 | 1.53 | 10.0 | 3.9 | 7.6 | 71.2 | 79 | 53 | 50 | 10 | 31 | 60 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.45 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 1 | 1 | 1 | 0 | 0.00 | .235 | 0.92 | 7.9 | 1.1 | 6.8 | 8.2 | 7 | 0 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1.88 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 31 | 0 | 2 | 5 | 2.65 | .333 | 1.47 | 7.8 | 5.6 | 4.6 | 37.1 | 32 | 17 | 11 | 8 | 23 | 19 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 6.73 |