| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 19 | 19 | 5 | 8 | 5.04 | .326 | 1.42 | 10.3 | 2.4 | 9.9 | 114.1 | 131 | 66 | 64 | 20 | 31 | 125 | 0 | 0 | 0 | 0 | 11 | 4 | 0 | 4.01 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 18 | 18 | 3 | 7 | 5.54 | .337 | 1.49 | 10.8 | 2.7 | 5.3 | 91.0 | 109 | 58 | 56 | 17 | 27 | 54 | 0 | 0 | 0 | 0 | 5 | 3 | 2 | 5.23 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 17 | 17 | 5 | 8 | 5.04 | .282 | 1.14 | 8.0 | 2.4 | 7.2 | 126.2 | 112 | 73 | 71 | 22 | 33 | 101 | 7 | 0 | 0 | 1 | 8 | 4 | 3 | 4.55 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 17 | 17 | 6 | 8 | 5.18 | .351 | 1.54 | 10.4 | 3.4 | 5.9 | 113.0 | 131 | 70 | 65 | 18 | 43 | 74 | 0 | 0 | 0 | 0 | 7 | 9 | 3 | 5.14 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 45 | 0 | 2 | 0 | 4.96 | .315 | 1.36 | 9.3 | 3.1 | 7.8 | 61.2 | 63 | 36 | 34 | 10 | 21 | 53 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 4.48 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 44 | 0 | 2 | 4 | 4.42 | .310 | 1.32 | 8.2 | 3.6 | 8.1 | 57.0 | 52 | 30 | 28 | 6 | 23 | 51 | 0 | 6 | 5 | 0 | 0 | 2 | 0 | 3.89 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 38 | 0 | 1 | 5 | 4.69 | .308 | 1.33 | 8.1 | 3.9 | 9.0 | 48.0 | 43 | 25 | 25 | 8 | 21 | 48 | 0 | 1 | 5 | 0 | 0 | 0 | 1 | 4.48 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 30 | 0 | 0 | 4 | 5.08 | .377 | 1.75 | 10.1 | 6.0 | 4.4 | 33.2 | 37 | 19 | 19 | 2 | 22 | 16 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 5.00 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 16 | 0 | 5 | 1 | 5.40 | .392 | 1.93 | 11.4 | 6.0 | 6.0 | 15.0 | 19 | 11 | 9 | 2 | 10 | 10 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.40 |