| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 12 | 12 | 4 | 6 | 3.95 | .305 | 1.30 | 7.9 | 3.8 | 9.4 | 82.0 | 72 | 36 | 36 | 7 | 35 | 86 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 3.33 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 11 | 11 | 3 | 4 | 3.86 | .284 | 1.15 | 7.9 | 2.5 | 8.6 | 72.1 | 63 | 39 | 31 | 13 | 20 | 69 | 0 | 0 | 0 | 0 | 5 | 3 | 3 | 4.39 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 34 | 0 | 2 | 0 | 4.06 | .250 | 0.94 | 6.4 | 2.0 | 9.3 | 31.0 | 22 | 14 | 14 | 5 | 7 | 32 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.90 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 42 | 17 | 0 | 1 | 0 | 2.30 | .277 | 1.15 | 6.0 | 4.8 | 12.6 | 15.2 | 10 | 4 | 4 | 1 | 8 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.67 |
| RP | Holland, A.Holland, Al >> | 31 | 1983 | L | 31 | 23 | 0 | 1 | 0 | 5.02 | .368 | 1.74 | 9.0 | 7.1 | 7.7 | 14.1 | 14 | 8 | 8 | 2 | 11 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.50 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 12 | 0 | 1 | 0 | 2.25 | .273 | 1.13 | 2.8 | 7.3 | 6.2 | 16.0 | 5 | 4 | 4 | 1 | 13 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.88 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 19 | 0 | 0 | 1 | 0.93 | .256 | 1.03 | 4.3 | 5.2 | 11.4 | 19.1 | 9 | 3 | 2 | 0 | 11 | 24 | 0 | 17 | 0 | 0 | 0 | 0 | 1 | 2.21 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 4 | 0 | 0 | 0 | 1.83 | .306 | 1.32 | 7.1 | 5.2 | 9.5 | 19.2 | 15 | 4 | 4 | 1 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.32 |