| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 21 | 21 | 7 | 8 | 3.72 | .289 | 1.18 | 8.5 | 2.2 | 5.1 | 135.1 | 127 | 57 | 56 | 14 | 33 | 77 | 2 | 0 | 0 | 0 | 11 | 5 | 1 | 4.05 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 22 | 22 | 7 | 10 | 5.67 | .353 | 1.63 | 11.0 | 3.7 | 9.0 | 100.0 | 122 | 74 | 63 | 21 | 41 | 100 | 0 | 0 | 0 | 0 | 9 | 1 | 3 | 4.99 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 20 | 20 | 4 | 7 | 6.36 | .366 | 1.72 | 12.1 | 3.4 | 5.9 | 75.0 | 101 | 53 | 53 | 14 | 28 | 49 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 5.28 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 22 | 21 | 5 | 10 | 5.96 | .354 | 1.63 | 11.3 | 3.5 | 5.9 | 90.2 | 113 | 62 | 60 | 12 | 35 | 59 | 1 | 1 | 0 | 0 | 6 | 1 | 4 | 4.62 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 47 | 24 | 18 | 3 | 14 | 5.97 | .357 | 1.64 | 11.8 | 3.0 | 5.5 | 98.0 | 128 | 68 | 65 | 12 | 33 | 60 | 0 | 2 | 0 | 0 | 5 | 2 | 1 | 4.44 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 60 | 0 | 3 | 4 | 5.83 | .340 | 1.51 | 8.0 | 5.6 | 9.4 | 75.2 | 67 | 50 | 49 | 13 | 47 | 78 | 0 | 11 | 5 | 0 | 0 | 3 | 4 | 5.17 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 60 | 0 | 1 | 3 | 5.48 | .327 | 1.41 | 9.0 | 3.8 | 8.3 | 67.1 | 67 | 41 | 41 | 10 | 28 | 62 | 0 | 4 | 2 | 0 | 0 | 3 | 0 | 4.48 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 70 | 0 | 4 | 2 | 5.20 | .338 | 1.49 | 9.6 | 3.8 | 9.7 | 90.0 | 96 | 56 | 52 | 15 | 38 | 97 | 0 | 0 | 2 | 0 | 0 | 4 | 0 | 4.41 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 60 | 0 | 3 | 2 | 4.46 | .300 | 1.27 | 8.2 | 3.3 | 8.5 | 78.2 | 71 | 40 | 39 | 11 | 29 | 74 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.09 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 58 | 0 | 3 | 2 | 5.69 | .345 | 1.55 | 8.5 | 5.5 | 5.0 | 91.2 | 86 | 65 | 58 | 13 | 56 | 51 | 0 | 1 | 1 | 0 | 0 | 3 | 4 | 5.68 |