| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 93 | 20 | 20 | 10 | 3 | 3.50 | .274 | 1.12 | 7.3 | 2.8 | 7.1 | 126.0 | 102 | 53 | 49 | 8 | 39 | 99 | 1 | 0 | 0 | 1 | 13 | 2 | 4 | 3.23 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 21 | 21 | 6 | 7 | 4.09 | .288 | 1.21 | 6.8 | 4.1 | 7.9 | 134.1 | 101 | 64 | 61 | 7 | 61 | 118 | 2 | 0 | 0 | 1 | 11 | 1 | 4 | 3.31 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 21 | 21 | 10 | 4 | 3.36 | .277 | 1.14 | 8.1 | 2.3 | 5.6 | 128.2 | 115 | 50 | 48 | 13 | 32 | 79 | 0 | 0 | 0 | 0 | 12 | 1 | 6 | 3.86 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 19 | 19 | 12 | 4 | 3.81 | .320 | 1.35 | 7.9 | 4.2 | 6.3 | 137.0 | 121 | 60 | 58 | 10 | 64 | 96 | 1 | 0 | 0 | 1 | 12 | 8 | 3 | 4.12 |
| RP | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 91 | 45 | 0 | 7 | 1 | 1.18 | .212 | 0.81 | 4.9 | 2.4 | 8.7 | 53.1 | 29 | 7 | 7 | 0 | 14 | 51 | 0 | 10 | 3 | 0 | 0 | 0 | 1 | 1.87 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 29 | 0 | 2 | 3 | 3.26 | .278 | 1.12 | 6.6 | 3.6 | 9.3 | 30.1 | 22 | 13 | 11 | 6 | 12 | 31 | 0 | 7 | 2 | 0 | 0 | 1 | 1 | 4.83 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 17 | 0 | 1 | 2 | 1.33 | .256 | 1.03 | 4.5 | 5.0 | 9.0 | 20.1 | 10 | 4 | 3 | 1 | 11 | 20 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 3.30 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 4 | 0 | 0 | 2 | 10.38 | .435 | 2.31 | 18.0 | 4.5 | 4.5 | 4.1 | 8 | 5 | 5 | 1 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.75 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 18 | 0 | 1 | 0 | 1.79 | .234 | 0.92 | 4.5 | 3.8 | 6.3 | 40.1 | 20 | 11 | 8 | 4 | 17 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.18 |