| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 95 | 28 | 28 | 10 | 10 | 4.77 | .302 | 1.28 | 9.3 | 2.2 | 5.0 | 186.2 | 193 | 111 | 99 | 23 | 46 | 103 | 5 | 0 | 0 | 0 | 14 | 3 | 4 | 4.29 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 27 | 27 | 11 | 11 | 4.51 | .295 | 1.21 | 8.8 | 2.1 | 6.0 | 175.2 | 172 | 93 | 88 | 29 | 41 | 116 | 4 | 0 | 0 | 1 | 13 | 7 | 4 | 4.65 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 86 | 26 | 26 | 6 | 10 | 6.03 | .361 | 1.65 | 8.9 | 6.0 | 6.6 | 122.1 | 121 | 83 | 82 | 22 | 81 | 90 | 0 | 0 | 0 | 0 | 8 | 5 | 6 | 5.98 |
| RP | Feirman, J.Feirman, Juan $$ >> | 25 | 2023 | R | 100 | 71 | 0 | 5 | 0 | 2.08 | .197 | 0.72 | 5.6 | 0.9 | 7.8 | 95.1 | 59 | 22 | 22 | 11 | 10 | 82 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 3.13 |
| RP | Strahm, M.Strahm, Matt >> | 32 | 2024 | L | 91 | 59 | 0 | 1 | 2 | 4.54 | .265 | 1.06 | 7.8 | 1.8 | 9.9 | 39.2 | 34 | 20 | 20 | 7 | 8 | 43 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.82 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 86 | 48 | 0 | 1 | 2 | 6.00 | .327 | 1.46 | 9.0 | 4.1 | 7.5 | 24.0 | 24 | 16 | 16 | 3 | 11 | 20 | 0 | 2 | 1 | 0 | 0 | 0 | 3 | 4.33 |
| RP | Gaddis, H.Gaddis, Hunter >> | 26 | 2024 | R | 85 | 68 | 0 | 1 | 1 | 2.66 | .228 | 0.85 | 5.6 | 2.1 | 6.1 | 47.1 | 29 | 15 | 14 | 4 | 11 | 32 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 3.57 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 89 | 59 | 0 | 3 | 2 | 3.46 | .286 | 1.20 | 7.0 | 4.0 | 9.0 | 41.2 | 32 | 16 | 16 | 6 | 18 | 41 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.22 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 83 | 38 | 0 | 1 | 3 | 3.00 | .278 | 1.15 | 8.3 | 2.1 | 9.7 | 39.0 | 36 | 16 | 13 | 6 | 9 | 42 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.54 |