| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 7 | 7 | 5 | 1 | 2.77 | .228 | 0.87 | 6.8 | 1.0 | 8.8 | 52.0 | 39 | 17 | 16 | 5 | 6 | 51 | 2 | 0 | 0 | 2 | 6 | 1 | 0 | 2.69 |
| SP | Kershaw, C.Kershaw, Clayton # $$ >> | 28 | 2016 | L | 100 | 8 | 8 | 3 | 2 | 4.31 | .276 | 1.10 | 8.3 | 1.7 | 7.9 | 48.0 | 44 | 28 | 23 | 9 | 9 | 42 | 1 | 0 | 0 | 0 | 4 | 2 | 1 | 4.38 |
| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 98 | 6 | 4 | 1 | 1 | 2.96 | .305 | 1.32 | 8.3 | 3.7 | 8.3 | 27.1 | 25 | 9 | 9 | 2 | 11 | 25 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3.33 |
| RP | Clase, E.Clase, Emmanuel >> | 26 | 2024 | R | 94 | 13 | 0 | 1 | 1 | 0.54 | .167 | 0.48 | 1.7 | 2.8 | 8.4 | 16.2 | 3 | 1 | 1 | 0 | 5 | 15 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 2.44 |
| RP | Miller, M.Miller, Mason >> | 25 | 2024 | R | 94 | 9 | 0 | 2 | 1 | 4.50 | .333 | 1.50 | 9.9 | 3.6 | 9.9 | 10.0 | 11 | 6 | 5 | 2 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.60 |
| RP | Phillips, C.Phillips, Connor >> | 24 | 2025 | R | 91 | 3 | 0 | 0 | 0 | 10.80 | .412 | 2.10 | 3.0 | 18.0 | 9.0 | 3.1 | 1 | 4 | 4 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 91 | 3 | 0 | 0 | 0 | 3.38 | .429 | 2.25 | 22.5 | 4.5 | 0.0 | 2.2 | 5 | 1 | 1 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 11.00 |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 95 | 2 | 0 | 0 | 1 | 0.77 | .239 | 0.94 | 7.4 | 1.6 | 8.2 | 11.2 | 9 | 1 | 1 | 0 | 2 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.73 |