| SP | Jones, S.Jones, Slim # $$ >> | 21 | 1934 | L | 84 | 29 | 29 | 14 | 9 | 3.96 | .305 | 1.30 | 9.1 | 2.6 | 6.3 | 193.1 | 195 | 86 | 85 | 20 | 56 | 135 | 5 | 0 | 0 | 1 | 18 | 4 | 1 | 3.88 |
| SP | Koufax, S.Koufax, Sandy $ >> | 30 | 1965 | L | 99 | 28 | 28 | 18 | 6 | 2.52 | .252 | 0.99 | 6.7 | 2.2 | 8.2 | 214.1 | 159 | 60 | 60 | 19 | 53 | 196 | 15 | 0 | 0 | 5 | 22 | 5 | 3 | 3.14 |
| SP | Javier, C.Javier, Cristian >> | 25 | 2022 | R | 92 | 27 | 27 | 6 | 9 | 4.80 | .305 | 1.27 | 8.3 | 3.1 | 8.9 | 135.0 | 125 | 73 | 72 | 23 | 46 | 134 | 0 | 0 | 0 | 0 | 8 | 7 | 3 | 4.41 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 92 | 27 | 27 | 10 | 9 | 4.85 | .305 | 1.25 | 8.4 | 2.9 | 8.0 | 161.1 | 151 | 87 | 87 | 23 | 51 | 143 | 1 | 0 | 0 | 0 | 13 | 10 | 2 | 4.22 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 91 | 27 | 26 | 8 | 11 | 5.42 | .308 | 1.33 | 9.3 | 2.6 | 7.5 | 161.0 | 167 | 97 | 97 | 22 | 47 | 135 | 1 | 0 | 0 | 0 | 9 | 1 | 2 | 3.99 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 94 | 75 | 0 | 7 | 2 | 2.83 | .286 | 1.17 | 7.0 | 3.6 | 7.9 | 101.2 | 79 | 32 | 32 | 12 | 40 | 89 | 0 | 8 | 2 | 0 | 0 | 3 | 0 | 4.06 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 96 | 39 | 0 | 3 | 0 | 4.66 | .318 | 1.37 | 10.7 | 1.9 | 8.3 | 38.2 | 45 | 21 | 20 | 6 | 8 | 35 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 3.92 |
| RP | Hudson, B.Hudson, Bryan >> | 27 | 2024 | L | 93 | 37 | 0 | 3 | 3 | 4.11 | .313 | 1.37 | 8.0 | 4.3 | 7.8 | 46.0 | 41 | 23 | 21 | 6 | 22 | 40 | 0 | 9 | 1 | 0 | 0 | 0 | 0 | 4.39 |