| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 97 | 20 | 20 | 5 | 10 | 4.29 | .309 | 1.30 | 8.7 | 3.0 | 5.3 | 130.0 | 126 | 64 | 62 | 17 | 43 | 77 | 3 | 0 | 0 | 2 | 11 | 5 | 3 | 4.62 |
| SP | Ryan, N.Ryan, Nolan $$ >> | 44 | 1991 | R | 89 | 19 | 19 | 7 | 7 | 3.22 | .297 | 1.24 | 7.0 | 4.2 | 7.5 | 128.2 | 99 | 52 | 46 | 13 | 60 | 107 | 0 | 0 | 0 | 0 | 10 | 4 | 4 | 4.15 |
| SP | Brown, M.Brown, Mordecai $ >> | 33 | 1909 | R | 87 | 19 | 19 | 6 | 5 | 4.39 | .309 | 1.30 | 9.4 | 2.4 | 5.3 | 125.0 | 130 | 64 | 61 | 12 | 33 | 73 | 2 | 0 | 0 | 1 | 9 | 5 | 1 | 3.99 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 80 | 19 | 19 | 5 | 11 | 4.10 | .308 | 1.30 | 8.6 | 3.1 | 6.4 | 125.0 | 120 | 67 | 57 | 15 | 43 | 89 | 5 | 0 | 0 | 1 | 10 | 4 | 3 | 4.26 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 56 | 0 | 5 | 4 | 3.27 | .259 | 1.01 | 6.7 | 2.4 | 8.6 | 74.1 | 55 | 28 | 27 | 11 | 20 | 71 | 0 | 5 | 3 | 0 | 0 | 3 | 2 | 3.95 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 92 | 49 | 0 | 3 | 4 | 4.07 | .311 | 1.34 | 8.5 | 3.6 | 8.7 | 55.1 | 52 | 25 | 25 | 5 | 22 | 53 | 0 | 6 | 5 | 0 | 0 | 1 | 1 | 3.51 |
| RP | Minter, A.Minter, A.J. >> | 28 | 2022 | L | 82 | 31 | 0 | 2 | 3 | 1.18 | .189 | 0.68 | 4.0 | 2.2 | 7.4 | 45.2 | 20 | 6 | 6 | 0 | 11 | 37 | 0 | 4 | 0 | 0 | 0 | 1 | 4 | 2.16 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 80 | 24 | 0 | 0 | 1 | 5.95 | .366 | 1.68 | 12.8 | 2.8 | 7.1 | 19.2 | 27 | 13 | 13 | 3 | 6 | 15 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.58 |
| RP | Harris, G.Harris, Greg >> | 30 | 1985 | R | 71 | 14 | 0 | 1 | 2 | 4.58 | .379 | 1.78 | 9.0 | 7.6 | 5.7 | 19.2 | 19 | 10 | 10 | 1 | 16 | 12 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 5.11 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 98 | 2 | 0 | 0 | 1 | 7.71 | .364 | 1.71 | 13.5 | 4.5 | 13.5 | 2.1 | 3 | 2 | 2 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.50 |
| RP | Helsley, R.Helsley, Ryan >> | 27 | 2022 | R | 99 | 4 | 0 | 0 | 0 | 4.91 | .421 | 2.18 | 21.0 | 3.0 | 9.0 | 3.2 | 7 | 2 | 2 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.33 |