| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 98 | 14 | 14 | 4 | 8 | 4.44 | .284 | 1.18 | 8.4 | 2.2 | 7.8 | 97.1 | 91 | 50 | 48 | 15 | 24 | 84 | 6 | 0 | 0 | 0 | 6 | 1 | 2 | 4.05 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 73 | 14 | 14 | 5 | 6 | 4.07 | .311 | 1.35 | 9.2 | 3.0 | 3.6 | 97.1 | 99 | 48 | 44 | 4 | 32 | 39 | 3 | 0 | 0 | 0 | 8 | 1 | 0 | 3.75 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 13 | 13 | 3 | 4 | 4.23 | .301 | 1.28 | 8.5 | 3.1 | 3.9 | 76.2 | 72 | 37 | 36 | 8 | 26 | 33 | 0 | 0 | 0 | 0 | 9 | 1 | 3 | 4.57 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 47 | 13 | 13 | 0 | 7 | 7.44 | .386 | 1.85 | 12.5 | 4.3 | 5.4 | 65.1 | 90 | 58 | 54 | 8 | 31 | 39 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 4.92 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 44 | 0 | 4 | 1 | 5.43 | .276 | 1.14 | 6.3 | 4.0 | 7.8 | 61.1 | 43 | 38 | 37 | 11 | 27 | 53 | 0 | 2 | 4 | 0 | 0 | 0 | 2 | 4.93 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 38 | 0 | 4 | 0 | 5.01 | .324 | 1.44 | 11.0 | 2.2 | 6.7 | 46.2 | 56 | 26 | 26 | 7 | 11 | 34 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.22 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 29 | 0 | 2 | 6 | 5.23 | .316 | 1.32 | 7.5 | 4.4 | 4.1 | 31.0 | 26 | 19 | 18 | 2 | 15 | 14 | 0 | 4 | 3 | 0 | 0 | 2 | 2 | 4.58 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 54 | 19 | 0 | 1 | 1 | 6.05 | .408 | 2.07 | 14.2 | 4.7 | 12.3 | 19.1 | 30 | 14 | 13 | 1 | 10 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 2.53 |