| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 24 | 24 | 7 | 14 | 3.82 | .283 | 1.14 | 8.0 | 2.3 | 4.4 | 165.0 | 146 | 79 | 70 | 20 | 42 | 80 | 7 | 0 | 0 | 1 | 13 | 7 | 2 | 4.50 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 23 | 23 | 10 | 9 | 3.99 | .303 | 1.28 | 7.8 | 3.7 | 4.9 | 162.1 | 141 | 74 | 72 | 18 | 67 | 88 | 5 | 0 | 0 | 1 | 11 | 4 | 8 | 4.67 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 23 | 23 | 7 | 9 | 4.26 | .309 | 1.31 | 9.4 | 2.3 | 3.9 | 131.0 | 137 | 62 | 62 | 16 | 34 | 57 | 2 | 0 | 0 | 2 | 13 | 5 | 0 | 4.61 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 22 | 22 | 2 | 13 | 6.23 | .336 | 1.50 | 10.2 | 3.4 | 5.2 | 124.1 | 140 | 87 | 86 | 25 | 47 | 71 | 2 | 0 | 0 | 0 | 5 | 2 | 2 | 5.66 |
| RP | Feliz, N.Feliz, Neftali # >> | 21 | 2009 | R | 97 | 67 | 0 | 2 | 4 | 5.29 | .329 | 1.46 | 8.0 | 5.2 | 8.2 | 81.2 | 72 | 50 | 48 | 6 | 47 | 74 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 3.91 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 51 | 0 | 3 | 0 | 3.73 | .327 | 1.43 | 8.4 | 4.5 | 7.8 | 60.1 | 56 | 26 | 25 | 11 | 30 | 52 | 0 | 3 | 1 | 0 | 0 | 2 | 4 | 5.25 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 41 | 0 | 2 | 1 | 3.07 | .290 | 1.23 | 8.4 | 2.7 | 5.7 | 44.0 | 41 | 16 | 15 | 6 | 13 | 28 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.39 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 31 | 0 | 3 | 1 | 7.85 | .394 | 1.88 | 11.9 | 5.5 | 10.0 | 28.2 | 37 | 25 | 25 | 4 | 17 | 31 | 0 | 0 | 2 | 0 | 0 | 2 | 2 | 4.68 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 19 | 0 | 0 | 3 | 6.21 | .341 | 1.52 | 10.6 | 3.1 | 5.6 | 29.0 | 34 | 21 | 20 | 4 | 10 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.69 |