| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 7 | 4 | 2.42 | .234 | 0.89 | 6.1 | 1.9 | 9.2 | 145.1 | 99 | 42 | 39 | 12 | 31 | 148 | 0 | 0 | 0 | 0 | 17 | 3 | 0 | 2.74 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 12 | 9 | 3 | 2 | 2.76 | .279 | 1.14 | 6.7 | 3.7 | 7.4 | 71.2 | 53 | 22 | 22 | 4 | 29 | 58 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 3.37 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 20 | 20 | 11 | 4 | 4.63 | .302 | 1.28 | 9.0 | 2.6 | 8.0 | 130.1 | 130 | 68 | 67 | 16 | 37 | 115 | 0 | 0 | 0 | 0 | 10 | 2 | 3 | 3.73 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 20 | 20 | 6 | 8 | 4.83 | .323 | 1.41 | 9.7 | 3.1 | 4.3 | 132.1 | 142 | 72 | 71 | 16 | 45 | 63 | 2 | 0 | 0 | 0 | 12 | 2 | 3 | 4.69 |
| SP | Newhouser, H.Newhouser, Hal >> | 25 | 1946 | L | 30 | 20 | 19 | 11 | 5 | 3.71 | .299 | 1.27 | 7.6 | 3.8 | 5.5 | 133.1 | 113 | 59 | 55 | 9 | 56 | 82 | 0 | 0 | 0 | 0 | 12 | 2 | 4 | 3.95 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 32 | 0 | 3 | 1 | 5.28 | .331 | 1.45 | 9.3 | 3.7 | 7.8 | 29.0 | 30 | 18 | 17 | 2 | 12 | 25 | 0 | 2 | 5 | 0 | 0 | 1 | 0 | 3.52 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 30 | 0 | 1 | 0 | 3.76 | .282 | 1.14 | 9.0 | 1.4 | 5.9 | 26.1 | 26 | 11 | 11 | 4 | 4 | 17 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.27 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 24 | 0 | 3 | 1 | 2.03 | .250 | 0.97 | 5.2 | 3.5 | 7.8 | 31.0 | 18 | 7 | 7 | 1 | 12 | 27 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.94 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 24 | 0 | 1 | 1 | 1.80 | .256 | 1.03 | 5.4 | 3.9 | 5.7 | 30.0 | 18 | 6 | 6 | 4 | 13 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.77 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 31 | 7 | 0 | 1 | 1 | 1.04 | .278 | 1.15 | 5.6 | 5.6 | 10.1 | 8.2 | 5 | 1 | 1 | 0 | 5 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.63 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 22 | 0 | 2 | 1 | 2.59 | .311 | 1.36 | 6.4 | 6.0 | 7.9 | 24.1 | 17 | 7 | 7 | 0 | 16 | 21 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.25 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 6 | 0 | 1 | 0 | 1.61 | .229 | 0.89 | 4.2 | 3.9 | 2.9 | 28.0 | 13 | 5 | 5 | 2 | 12 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.57 |