| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 23 | 23 | 10 | 7 | 2.88 | .261 | 1.04 | 6.8 | 2.5 | 7.9 | 159.1 | 121 | 51 | 51 | 14 | 44 | 140 | 2 | 0 | 0 | 1 | 16 | 4 | 0 | 3.29 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 22 | 22 | 11 | 9 | 3.84 | .293 | 1.22 | 9.1 | 1.9 | 4.8 | 164.0 | 166 | 70 | 70 | 12 | 34 | 87 | 6 | 0 | 0 | 4 | 11 | 4 | 3 | 3.59 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 21 | 21 | 8 | 6 | 4.51 | .299 | 1.25 | 8.4 | 2.9 | 6.7 | 159.2 | 148 | 81 | 80 | 19 | 51 | 119 | 5 | 0 | 0 | 1 | 11 | 5 | 6 | 4.11 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 58 | 21 | 21 | 2 | 8 | 5.53 | .340 | 1.52 | 9.5 | 4.3 | 8.1 | 84.2 | 89 | 56 | 52 | 9 | 40 | 76 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 4.08 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 54 | 0 | 10 | 0 | 3.52 | .237 | 0.93 | 6.2 | 2.3 | 10.6 | 79.1 | 54 | 31 | 31 | 10 | 20 | 93 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 3.05 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 51 | 0 | 4 | 3 | 3.48 | .316 | 1.35 | 5.8 | 6.4 | 10.2 | 62.0 | 40 | 24 | 24 | 5 | 44 | 70 | 0 | 6 | 4 | 0 | 0 | 2 | 0 | 4.02 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 36 | 0 | 1 | 4 | 4.97 | .313 | 1.32 | 7.8 | 4.0 | 9.2 | 38.0 | 33 | 22 | 21 | 6 | 17 | 39 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 4.50 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 16 | 0 | 2 | 2 | 5.96 | .346 | 1.59 | 11.9 | 2.9 | 5.3 | 22.2 | 29 | 15 | 15 | 7 | 7 | 13 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.91 |