| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 23 | 23 | 6 | 9 | 4.50 | .320 | 1.39 | 9.8 | 2.8 | 5.0 | 132.0 | 143 | 71 | 66 | 14 | 41 | 74 | 0 | 0 | 0 | 0 | 12 | 2 | 1 | 4.23 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 22 | 22 | 9 | 6 | 4.05 | .297 | 1.23 | 8.7 | 2.3 | 7.2 | 131.0 | 127 | 62 | 59 | 13 | 34 | 105 | 0 | 0 | 0 | 0 | 11 | 5 | 1 | 3.58 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 21 | 21 | 12 | 6 | 3.86 | .299 | 1.26 | 8.6 | 2.8 | 5.0 | 126.0 | 120 | 57 | 54 | 9 | 39 | 70 | 0 | 0 | 0 | 0 | 13 | 2 | 3 | 3.79 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 21 | 21 | 7 | 9 | 4.06 | .290 | 1.22 | 9.1 | 2.0 | 4.4 | 128.2 | 129 | 64 | 58 | 13 | 28 | 62 | 0 | 0 | 0 | 0 | 10 | 1 | 2 | 4.03 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 21 | 21 | 6 | 7 | 4.25 | .314 | 1.34 | 9.4 | 2.7 | 5.3 | 131.1 | 137 | 66 | 62 | 14 | 39 | 77 | 4 | 0 | 0 | 1 | 11 | 4 | 5 | 4.20 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 41 | 0 | 2 | 1 | 3.26 | .305 | 1.29 | 7.6 | 4.3 | 8.1 | 38.2 | 32 | 14 | 14 | 2 | 18 | 34 | 0 | 29 | 5 | 0 | 0 | 1 | 0 | 3.39 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 32 | 0 | 4 | 1 | 4.12 | .276 | 1.12 | 7.4 | 2.8 | 5.5 | 39.1 | 32 | 18 | 18 | 4 | 12 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 60 | 0 | 4 | 3 | 4.39 | .337 | 1.49 | 8.2 | 5.4 | 9.0 | 67.2 | 61 | 34 | 33 | 6 | 40 | 67 | 0 | 0 | 4 | 0 | 0 | 2 | 12 | 4.04 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 49 | 0 | 4 | 0 | 3.41 | .323 | 1.43 | 8.5 | 4.3 | 8.1 | 58.0 | 55 | 22 | 22 | 3 | 28 | 52 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.33 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 21 | 0 | 1 | 1 | 3.74 | .343 | 1.52 | 7.3 | 6.9 | 9.4 | 21.2 | 17 | 12 | 9 | 1 | 16 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.95 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 38 | 0 | 4 | 2 | 4.95 | .351 | 1.60 | 10.1 | 4.3 | 8.6 | 40.0 | 45 | 27 | 22 | 7 | 19 | 38 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 4.88 |