| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 100 | 38 | 38 | 17 | 14 | 3.29 | .285 | 1.19 | 8.1 | 2.6 | 10.1 | 254.2 | 229 | 99 | 93 | 20 | 73 | 285 | 2 | 0 | 0 | 0 | 27 | 3 | 4 | 2.68 |
| SP | Lohse, K.Lohse, Kyle # >> | 33 | 2011 | R | 83 | 35 | 35 | 11 | 17 | 4.62 | .322 | 1.40 | 9.5 | 3.1 | 4.9 | 218.0 | 229 | 118 | 112 | 25 | 76 | 119 | 2 | 0 | 0 | 1 | 17 | 5 | 4 | 4.51 |
| SP | Moyer, J.Moyer, Jamie # >> | 36 | 1998 | L | 74 | 34 | 34 | 13 | 8 | 4.86 | .326 | 1.43 | 10.8 | 2.1 | 5.9 | 201.2 | 241 | 115 | 109 | 19 | 47 | 132 | 3 | 0 | 0 | 1 | 17 | 4 | 6 | 3.68 |
| RP | Speier, G.Speier, Gabe >> | 30 | 2025 | L | 99 | 88 | 0 | 6 | 2 | 3.59 | .263 | 1.05 | 7.5 | 2.0 | 7.6 | 107.2 | 89 | 46 | 43 | 10 | 24 | 90 | 0 | 3 | 2 | 0 | 0 | 2 | 4 | 3.26 |
| RP | Martinez, T.Martinez, Tippy >> | 33 | 1983 | L | 81 | 69 | 0 | 3 | 1 | 2.53 | .298 | 1.26 | 7.2 | 4.2 | 5.7 | 92.2 | 74 | 29 | 26 | 5 | 43 | 58 | 0 | 5 | 5 | 0 | 0 | 1 | 4 | 3.88 |
| RP | Cimber, A.Cimber, Adam >> | 30 | 2021 | R | 77 | 40 | 0 | 5 | 6 | 5.08 | .364 | 1.67 | 11.8 | 3.2 | 6.7 | 39.0 | 51 | 22 | 22 | 1 | 14 | 29 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.08 |
| RP | Henneman, M.Henneman, Mike >> | 26 | 1987 | R | 65 | 24 | 0 | 2 | 2 | 3.33 | .243 | 0.96 | 5.7 | 3.0 | 4.3 | 27.0 | 17 | 10 | 10 | 4 | 9 | 13 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.96 |
| RP | Fraser, W.Fraser, Willie >> | 26 | 1990 | R | 56 | 24 | 0 | 1 | 0 | 4.99 | .270 | 1.11 | 6.3 | 3.9 | 4.5 | 30.2 | 21 | 17 | 17 | 2 | 13 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.17 |
| SP | Candelaria, J.Candelaria, John >> | 25 | 1978 | L | 49 | 27 | 0 | 6 | 1 | 4.83 | .345 | 1.56 | 11.6 | 2.5 | 4.2 | 123.0 | 158 | 68 | 66 | 12 | 34 | 58 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.20 |
| CL | Andersen, L.Andersen, Larry >> | 36 | 1989 | R | 87 | 58 | 0 | 7 | 4 | 1.15 | .260 | 1.05 | 6.8 | 2.7 | 5.7 | 70.1 | 53 | 10 | 9 | 4 | 21 | 44 | 0 | 28 | 1 | 0 | 0 | 0 | 1 | 3.39 |