| SP | Waddell, R.Waddell, Rube >> | 32 | 1908 | L | 95 | 36 | 36 | 13 | 15 | 3.38 | .291 | 1.22 | 7.8 | 3.2 | 6.2 | 258.1 | 224 | 109 | 97 | 17 | 91 | 178 | 2 | 0 | 0 | 0 | 25 | 3 | 3 | 3.57 |
| SP | Astacio, P.Astacio, Pedro >> | 24 | 1993 | R | 78 | 34 | 34 | 12 | 13 | 4.52 | .332 | 1.45 | 9.2 | 3.9 | 5.0 | 207.0 | 212 | 113 | 104 | 14 | 89 | 114 | 0 | 0 | 0 | 0 | 19 | 8 | 13 | 4.18 |
| SP | Hendrix, C.Hendrix, Claude >> | 28 | 1917 | R | 56 | 33 | 33 | 10 | 11 | 4.14 | .314 | 1.35 | 9.4 | 2.8 | 5.5 | 189.1 | 198 | 103 | 87 | 18 | 58 | 115 | 0 | 0 | 0 | 0 | 12 | 4 | 5 | 4.01 |
| SP | McHugh, C.McHugh, Collin # >> | 28 | 2015 | R | 52 | 31 | 31 | 13 | 9 | 4.54 | .324 | 1.40 | 10.4 | 2.3 | 6.0 | 210.1 | 242 | 119 | 106 | 25 | 53 | 141 | 1 | 0 | 0 | 0 | 16 | 7 | 4 | 4.06 |
| SP | Fernandez, A.Fernandez, Alex # >> | 22 | 1991 | R | 42 | 31 | 31 | 10 | 11 | 4.88 | .336 | 1.51 | 9.3 | 4.3 | 5.8 | 179.0 | 184 | 104 | 97 | 13 | 86 | 115 | 0 | 0 | 0 | 0 | 10 | 2 | 2 | 4.13 |
| RP | Balfour, G.Balfour, Grant >> | 35 | 2012 | R | 95 | 93 | 0 | 2 | 6 | 2.03 | .256 | 1.03 | 6.2 | 3.2 | 6.4 | 137.2 | 94 | 33 | 31 | 5 | 48 | 97 | 0 | 7 | 6 | 0 | 0 | 0 | 4 | 3.11 |
| RP | Stephenson, R.Stephenson, Robert >> | 28 | 2021 | R | 51 | 65 | 0 | 3 | 5 | 3.38 | .325 | 1.43 | 8.6 | 4.4 | 9.2 | 74.2 | 71 | 30 | 28 | 8 | 36 | 76 | 0 | 4 | 3 | 0 | 0 | 1 | 5 | 3.85 |
| RP | Axford, J.Axford, John >> | 29 | 2012 | R | 41 | 59 | 0 | 8 | 3 | 3.50 | .365 | 1.70 | 9.7 | 5.7 | 7.7 | 54.0 | 58 | 25 | 21 | 4 | 34 | 46 | 0 | 4 | 1 | 0 | 0 | 1 | 5 | 4.20 |
| SP | Leonard, D.Leonard, Dutch >> | 32 | 1941 | R | 40 | 2 | 2 | 1 | 1 | 4.11 | .303 | 1.30 | 8.4 | 3.6 | 4.2 | 15.1 | 14 | 9 | 7 | 4 | 6 | 7 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 6.73 |
| SP | Kershaw, C.Kershaw, Clayton >> | 20 | 2008 | L | 30 | 13 | 0 | 2 | 1 | 1.17 | .270 | 1.11 | 7.8 | 2.4 | 7.8 | 15.1 | 13 | 2 | 2 | 1 | 4 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.93 |