| SP | Koufax, S.Koufax, Sandy $$ >> | 30 | 1965 | L | 98 | 27 | 27 | 11 | 9 | 4.34 | .311 | 1.32 | 8.5 | 3.4 | 8.3 | 192.2 | 182 | 104 | 93 | 23 | 73 | 177 | 2 | 0 | 0 | 2 | 12 | 6 | 1 | 3.95 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 26 | 26 | 12 | 10 | 3.84 | .297 | 1.24 | 8.6 | 2.6 | 5.7 | 189.2 | 181 | 89 | 81 | 22 | 54 | 119 | 3 | 0 | 0 | 1 | 15 | 5 | 5 | 4.19 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 25 | 25 | 6 | 10 | 5.18 | .331 | 1.47 | 9.8 | 3.5 | 7.8 | 158.0 | 172 | 102 | 91 | 18 | 61 | 137 | 1 | 0 | 0 | 0 | 12 | 1 | 10 | 3.92 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 76 | 25 | 25 | 9 | 11 | 4.40 | .308 | 1.30 | 9.1 | 2.6 | 5.0 | 184.0 | 186 | 110 | 90 | 32 | 54 | 103 | 9 | 0 | 0 | 0 | 13 | 6 | 5 | 5.12 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 26 | 25 | 11 | 9 | 5.14 | .340 | 1.51 | 10.7 | 2.9 | 5.2 | 171.2 | 204 | 107 | 98 | 25 | 56 | 98 | 3 | 0 | 0 | 0 | 11 | 5 | 6 | 4.82 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 43 | 0 | 1 | 2 | 1.43 | .267 | 1.07 | 6.5 | 3.1 | 7.4 | 44.0 | 32 | 8 | 7 | 1 | 15 | 36 | 0 | 26 | 3 | 0 | 0 | 1 | 0 | 2.75 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 65 | 0 | 6 | 4 | 2.76 | .302 | 1.28 | 7.5 | 4.2 | 8.2 | 71.2 | 59 | 23 | 22 | 5 | 33 | 65 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.52 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 53 | 0 | 7 | 2 | 3.25 | .284 | 1.16 | 8.5 | 2.0 | 7.4 | 55.1 | 52 | 24 | 20 | 7 | 12 | 45 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 3.78 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 32 | 0 | 4 | 2 | 6.04 | .366 | 1.66 | 11.9 | 3.2 | 9.0 | 28.1 | 37 | 20 | 19 | 6 | 10 | 28 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 5.07 |