| SP | Ryan, N.Ryan, Nolan # $$ >> | 44 | 1991 | R | 73 | 33 | 33 | 12 | 14 | 3.67 | .287 | 1.19 | 6.7 | 4.0 | 8.3 | 218.0 | 162 | 94 | 89 | 24 | 98 | 201 | 4 | 0 | 0 | 3 | 20 | 3 | 14 | 3.98 |
| SP | Verlander, J.Verlander, Justin $$ >> | 36 | 2019 | R | 99 | 34 | 34 | 13 | 11 | 3.45 | .294 | 1.22 | 8.1 | 2.9 | 8.9 | 224.1 | 201 | 92 | 86 | 24 | 73 | 222 | 1 | 0 | 0 | 0 | 25 | 6 | 2 | 3.47 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 32 | 32 | 11 | 11 | 3.79 | .299 | 1.25 | 7.9 | 3.3 | 5.6 | 197.0 | 174 | 93 | 83 | 18 | 73 | 123 | 0 | 0 | 0 | 0 | 19 | 5 | 2 | 4.13 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 32 | 32 | 12 | 9 | 4.84 | .315 | 1.35 | 9.1 | 3.1 | 4.7 | 206.1 | 209 | 114 | 111 | 23 | 70 | 108 | 3 | 0 | 0 | 0 | 16 | 6 | 1 | 4.51 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 28 | 28 | 9 | 11 | 5.56 | .332 | 1.46 | 10.1 | 3.1 | 4.9 | 179.2 | 201 | 124 | 111 | 30 | 61 | 98 | 2 | 0 | 0 | 0 | 9 | 6 | 4 | 5.21 |
| RP | Gossage, R.Gossage, Rich † >> | 30 | 1981 | R | 90 | 81 | 0 | 11 | 5 | 3.19 | .276 | 1.10 | 6.5 | 3.5 | 7.6 | 118.2 | 85 | 45 | 42 | 15 | 46 | 100 | 0 | 0 | 3 | 0 | 0 | 5 | 2 | 4.25 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 39 | 0 | 5 | 2 | 1.79 | .257 | 1.04 | 5.0 | 4.4 | 11.0 | 45.1 | 25 | 9 | 9 | 4 | 22 | 55 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 3.18 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 28 | 0 | 2 | 2 | 2.45 | .286 | 1.17 | 7.0 | 3.8 | 8.8 | 36.2 | 28 | 13 | 10 | 1 | 15 | 35 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 2.75 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 59 | 0 | 0 | 3 | 3.79 | .293 | 1.17 | 6.0 | 4.7 | 10.3 | 54.2 | 36 | 25 | 23 | 5 | 28 | 62 | 0 | 46 | 5 | 0 | 0 | 4 | 2 | 3.69 |
| SU | Eckersley, D.Eckersley, Dennis $$ >> | 36 | 1990 | R | 87 | 61 | 0 | 2 | 0 | 1.78 | .270 | 1.10 | 7.3 | 2.6 | 6.9 | 65.2 | 53 | 13 | 13 | 2 | 19 | 50 | 0 | 6 | 3 | 0 | 0 | 1 | 0 | 2.78 |