| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 27 | 27 | 14 | 8 | 3.79 | .276 | 1.11 | 7.9 | 2.0 | 9.5 | 178.0 | 157 | 77 | 75 | 25 | 40 | 188 | 0 | 0 | 0 | 0 | 16 | 7 | 0 | 3.51 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 26 | 26 | 9 | 9 | 4.59 | .313 | 1.33 | 8.8 | 3.2 | 8.7 | 180.1 | 175 | 96 | 92 | 27 | 64 | 174 | 2 | 0 | 0 | 0 | 16 | 7 | 3 | 4.20 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 25 | 25 | 8 | 10 | 4.92 | .310 | 1.34 | 9.4 | 2.7 | 3.9 | 179.1 | 187 | 99 | 98 | 24 | 53 | 77 | 2 | 0 | 0 | 0 | 10 | 2 | 4 | 4.80 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 70 | 0 | 6 | 4 | 3.28 | .288 | 1.16 | 6.4 | 4.0 | 8.6 | 98.2 | 70 | 37 | 36 | 9 | 44 | 94 | 0 | 7 | 1 | 0 | 0 | 6 | 2 | 3.81 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 53 | 0 | 1 | 4 | 3.05 | .298 | 1.24 | 6.4 | 4.7 | 9.0 | 59.0 | 42 | 24 | 20 | 6 | 31 | 59 | 0 | 12 | 2 | 0 | 0 | 2 | 0 | 4.00 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 40 | 0 | 3 | 3 | 3.05 | .290 | 1.20 | 5.4 | 5.4 | 9.0 | 38.1 | 23 | 15 | 13 | 5 | 23 | 38 | 0 | 2 | 3 | 0 | 0 | 1 | 2 | 4.61 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 7 | 0 | 3 | 2 | 2.35 | .303 | 1.30 | 8.4 | 3.6 | 11.4 | 15.1 | 14 | 4 | 4 | 1 | 6 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.53 |