| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 91 | 18 | 18 | 5 | 8 | 4.97 | .321 | 1.38 | 9.3 | 3.1 | 10.5 | 112.1 | 116 | 69 | 62 | 21 | 39 | 131 | 2 | 0 | 0 | 0 | 8 | 4 | 2 | 4.25 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 78 | 18 | 18 | 1 | 14 | 9.39 | .420 | 2.13 | 14.7 | 4.6 | 5.9 | 84.1 | 137 | 105 | 88 | 30 | 43 | 55 | 0 | 0 | 0 | 0 | 3 | 3 | 6 | 7.98 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 18 | 17 | 3 | 6 | 6.08 | .353 | 1.64 | 11.2 | 3.6 | 6.9 | 97.2 | 121 | 71 | 66 | 14 | 39 | 74 | 0 | 0 | 0 | 0 | 7 | 0 | 3 | 4.56 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 18 | 17 | 7 | 7 | 5.14 | .340 | 1.53 | 9.1 | 4.7 | 9.3 | 103.1 | 104 | 68 | 59 | 13 | 54 | 106 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 4.21 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 98 | 48 | 0 | 8 | 1 | 4.50 | .300 | 1.27 | 8.9 | 2.6 | 9.8 | 60.0 | 59 | 39 | 30 | 10 | 17 | 65 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 3.90 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 42 | 0 | 2 | 2 | 3.18 | .314 | 1.37 | 9.0 | 3.4 | 7.8 | 51.0 | 51 | 26 | 18 | 6 | 19 | 44 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 3.92 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 27 | 0 | 1 | 0 | 3.00 | .349 | 1.58 | 9.8 | 4.4 | 11.2 | 33.0 | 36 | 14 | 11 | 4 | 16 | 41 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 56 | 24 | 0 | 1 | 0 | 3.69 | .291 | 1.23 | 7.0 | 4.4 | 12.5 | 31.2 | 24 | 15 | 13 | 3 | 15 | 43 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.94 |