| SP | Maddux, G.Maddux, Greg † $$ >> | 29 | 1995 | R | 90 | 18 | 18 | 10 | 6 | 2.93 | .273 | 1.10 | 7.8 | 2.1 | 6.3 | 135.0 | 117 | 47 | 44 | 9 | 32 | 94 | 4 | 0 | 0 | 2 | 11 | 3 | 4 | 3.25 |
| SP | Greinke, Z.Greinke, Zack † >> | 32 | 2015 | R | 94 | 18 | 18 | 11 | 3 | 2.78 | .281 | 1.15 | 7.3 | 3.1 | 7.2 | 129.1 | 104 | 42 | 40 | 6 | 45 | 103 | 3 | 0 | 0 | 2 | 14 | 3 | 2 | 3.12 |
| SP | Guidry, R.Guidry, Ron † >> | 28 | 1978 | L | 81 | 17 | 17 | 10 | 2 | 2.93 | .271 | 1.05 | 6.9 | 2.6 | 6.7 | 129.0 | 99 | 43 | 42 | 14 | 37 | 96 | 2 | 0 | 0 | 2 | 12 | 8 | 2 | 3.97 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 85 | 38 | 0 | 3 | 1 | 2.77 | .220 | 0.83 | 6.4 | 1.0 | 9.0 | 52.0 | 37 | 16 | 16 | 8 | 6 | 52 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 3.40 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 75 | 28 | 0 | 3 | 1 | 1.80 | .250 | 0.97 | 6.3 | 2.4 | 8.4 | 30.0 | 21 | 6 | 6 | 2 | 8 | 28 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2.90 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 14 | 0 | 3 | 1 | 3.55 | .224 | 0.79 | 4.5 | 3.0 | 9.0 | 12.2 | 6 | 5 | 5 | 3 | 4 | 12 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.50 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 84 | 37 | 0 | 3 | 6 | 4.02 | .275 | 1.12 | 7.4 | 2.7 | 8.3 | 40.1 | 33 | 19 | 18 | 5 | 12 | 37 | 0 | 20 | 3 | 0 | 0 | 1 | 0 | 3.75 |