| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 13 | 13 | 4 | 3 | 5.78 | .345 | 1.57 | 10.7 | 3.4 | 9.0 | 67.0 | 80 | 45 | 43 | 11 | 25 | 67 | 0 | 0 | 0 | 0 | 6 | 1 | 1 | 4.30 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 69 | 13 | 13 | 6 | 4 | 3.10 | .300 | 1.27 | 7.6 | 3.9 | 5.9 | 107.1 | 90 | 40 | 37 | 6 | 46 | 70 | 4 | 0 | 0 | 2 | 9 | 2 | 3 | 3.77 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 67 | 13 | 13 | 5 | 6 | 4.05 | .318 | 1.36 | 9.0 | 3.3 | 9.5 | 80.0 | 80 | 37 | 36 | 8 | 29 | 84 | 1 | 0 | 0 | 1 | 6 | 3 | 2 | 3.40 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 63 | 12 | 12 | 4 | 4 | 4.56 | .295 | 1.24 | 8.9 | 2.3 | 7.1 | 71.0 | 70 | 37 | 36 | 12 | 18 | 56 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 4.42 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 33 | 0 | 1 | 2 | 4.50 | .273 | 1.10 | 6.4 | 3.6 | 8.3 | 48.0 | 34 | 24 | 24 | 8 | 19 | 44 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 4.58 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 93 | 34 | 0 | 4 | 1 | 2.40 | .283 | 1.19 | 5.0 | 5.7 | 10.3 | 41.1 | 23 | 11 | 11 | 4 | 26 | 47 | 0 | 3 | 2 | 0 | 0 | 0 | 8 | 3.88 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 30 | 0 | 1 | 2 | 3.58 | .279 | 1.13 | 4.8 | 5.6 | 7.6 | 32.2 | 17 | 13 | 13 | 4 | 20 | 27 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 4.91 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 74 | 16 | 0 | 1 | 1 | 1.80 | .277 | 1.15 | 7.2 | 3.2 | 6.3 | 20.0 | 16 | 4 | 4 | 0 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.65 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 11 | 0 | 0 | 3 | 5.68 | .296 | 1.26 | 5.3 | 6.8 | 15.8 | 12.2 | 7 | 8 | 8 | 1 | 9 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2.83 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 62 | 8 | 0 | 0 | 0 | 7.20 | .318 | 1.40 | 9.9 | 2.7 | 9.9 | 10.0 | 11 | 8 | 8 | 2 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.30 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 58 | 5 | 0 | 0 | 0 | 9.64 | .462 | 2.57 | 22.5 | 4.5 | 6.8 | 4.2 | 10 | 5 | 5 | 0 | 2 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.00 |