| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 18 | 18 | 6 | 7 | 4.38 | .297 | 1.25 | 8.0 | 3.3 | 9.6 | 127.1 | 113 | 66 | 62 | 21 | 46 | 135 | 0 | 0 | 0 | 0 | 11 | 2 | 0 | 4.16 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 84 | 17 | 17 | 8 | 6 | 3.39 | .262 | 1.04 | 7.7 | 1.7 | 6.9 | 135.1 | 115 | 52 | 51 | 18 | 26 | 103 | 8 | 0 | 0 | 2 | 11 | 3 | 3 | 3.85 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 17 | 17 | 4 | 6 | 5.02 | .329 | 1.43 | 9.7 | 3.2 | 7.4 | 75.1 | 81 | 46 | 42 | 14 | 27 | 62 | 0 | 0 | 0 | 0 | 1 | 3 | 3 | 4.97 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 71 | 17 | 17 | 3 | 12 | 6.59 | .368 | 1.74 | 9.9 | 5.8 | 6.6 | 95.2 | 105 | 71 | 70 | 24 | 61 | 70 | 1 | 0 | 0 | 0 | 5 | 1 | 3 | 6.77 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 41 | 0 | 4 | 2 | 4.22 | .312 | 1.32 | 7.3 | 4.7 | 8.8 | 59.2 | 48 | 31 | 28 | 9 | 31 | 58 | 0 | 5 | 1 | 0 | 0 | 2 | 1 | 4.69 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 41 | 0 | 3 | 4 | 4.13 | .298 | 1.25 | 7.5 | 3.8 | 8.1 | 48.0 | 40 | 25 | 22 | 8 | 20 | 43 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.69 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 31 | 0 | 3 | 1 | 3.41 | .298 | 1.28 | 7.1 | 4.3 | 8.4 | 29.0 | 23 | 15 | 11 | 6 | 14 | 27 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 5.28 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 25 | 0 | 1 | 2 | 7.25 | .385 | 1.88 | 9.4 | 7.8 | 10.6 | 22.1 | 23 | 18 | 18 | 4 | 19 | 26 | 0 | 4 | 1 | 0 | 0 | 0 | 2 | 5.59 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 61 | 19 | 0 | 1 | 0 | 3.52 | .317 | 1.39 | 8.6 | 3.9 | 9.0 | 23.0 | 22 | 9 | 9 | 3 | 10 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.00 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 56 | 4 | 0 | 0 | 0 | 9.00 | .417 | 2.14 | 15.4 | 3.9 | 9.0 | 7.0 | 12 | 7 | 7 | 2 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |