| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 18 | 18 | 4 | 8 | 5.93 | .331 | 1.45 | 10.2 | 2.9 | 9.3 | 95.2 | 108 | 65 | 63 | 15 | 31 | 98 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.06 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 18 | 17 | 4 | 7 | 4.45 | .317 | 1.36 | 8.8 | 3.4 | 5.5 | 89.0 | 87 | 45 | 44 | 10 | 34 | 54 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.49 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 73 | 18 | 17 | 3 | 9 | 7.08 | .372 | 1.73 | 11.7 | 4.0 | 6.8 | 87.2 | 113 | 74 | 69 | 14 | 39 | 66 | 3 | 0 | 0 | 0 | 5 | 4 | 0 | 5.06 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 64 | 17 | 17 | 5 | 6 | 4.95 | .340 | 1.51 | 10.3 | 3.4 | 6.2 | 103.2 | 118 | 59 | 57 | 23 | 39 | 71 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 5.75 |
| SP | Smoltz, J.Smoltz, John >> | 29 | 1996 | R | 62 | 19 | 17 | 6 | 4 | 5.68 | .333 | 1.47 | 10.0 | 3.2 | 8.6 | 95.0 | 106 | 63 | 60 | 18 | 34 | 91 | 1 | 1 | 0 | 0 | 7 | 2 | 4 | 4.68 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 59 | 0 | 2 | 2 | 4.02 | .290 | 1.21 | 8.0 | 3.0 | 10.9 | 71.2 | 63 | 32 | 32 | 11 | 24 | 86 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 3.65 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 47 | 0 | 2 | 2 | 3.96 | .319 | 1.39 | 9.3 | 3.2 | 9.3 | 61.1 | 63 | 27 | 27 | 8 | 22 | 63 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.77 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 55 | 0 | 5 | 6 | 6.17 | .349 | 1.56 | 9.2 | 4.8 | 10.8 | 54.0 | 55 | 37 | 37 | 13 | 29 | 65 | 0 | 4 | 3 | 0 | 0 | 3 | 5 | 5.50 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 39 | 0 | 3 | 5 | 6.62 | .332 | 1.43 | 9.2 | 3.9 | 11.1 | 51.2 | 52 | 38 | 38 | 13 | 22 | 63 | 0 | 4 | 2 | 0 | 0 | 3 | 2 | 5.31 |