| SP | Skenes, P.Skenes, Paul >> | 23 | 2025 | R | 95 | 34 | 34 | 14 | 9 | 3.51 | .291 | 1.22 | 8.6 | 2.5 | 9.8 | 202.1 | 192 | 83 | 79 | 28 | 55 | 219 | 1 | 0 | 0 | 1 | 20 | 2 | 5 | 3.48 |
| SP | Brown, H.Brown, Hunter † >> | 26 | 2025 | R | 92 | 33 | 33 | 15 | 10 | 3.85 | .311 | 1.34 | 8.6 | 3.5 | 10.5 | 189.1 | 180 | 88 | 81 | 19 | 74 | 220 | 0 | 0 | 0 | 0 | 20 | 2 | 0 | 3.19 |
| SP | Giolito, L.Giolito, Lucas # >> | 30 | 2025 | R | 45 | 23 | 23 | 6 | 11 | 5.72 | .358 | 1.64 | 10.8 | 4.1 | 8.0 | 113.1 | 135 | 77 | 72 | 18 | 51 | 100 | 0 | 0 | 0 | 0 | 8 | 4 | 4 | 4.76 |
| SP | Kelly, M.Kelly, Merrill # >> | 36 | 2025 | R | 74 | 32 | 31 | 12 | 11 | 4.06 | .313 | 1.35 | 9.2 | 3.1 | 8.3 | 168.2 | 171 | 83 | 76 | 22 | 57 | 154 | 0 | 0 | 0 | 0 | 16 | 3 | 2 | 3.94 |
| CL | Hader, J.Hader, Josh † >> | 31 | 2025 | L | 100 | 69 | 0 | 3 | 4 | 1.57 | .231 | 0.86 | 4.5 | 3.3 | 12.2 | 74.1 | 37 | 13 | 13 | 3 | 27 | 100 | 0 | 44 | 2 | 0 | 0 | 3 | 2 | 2.04 |
| RP | Gibson, C.Gibson, Cade >> | 27 | 2025 | L | 45 | 86 | 0 | 2 | 2 | 3.01 | .292 | 1.22 | 7.4 | 3.7 | 7.1 | 68.2 | 56 | 24 | 23 | 7 | 28 | 54 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 4.03 |
| RP | Holton, T.Holton, Tyler >> | 29 | 2025 | L | 59 | 50 | 0 | 2 | 2 | 4.12 | .302 | 1.27 | 8.5 | 3.0 | 6.5 | 39.1 | 37 | 19 | 18 | 6 | 13 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.64 |
| RP | Martin, C.Martin, Chris >> | 39 | 2025 | R | 38 | 42 | 0 | 1 | 2 | 4.22 | .238 | 0.94 | 6.2 | 2.3 | 9.8 | 32.0 | 22 | 18 | 15 | 3 | 8 | 35 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.78 |
| RP | Kahnle, T.Kahnle, Tommy >> | 35 | 2025 | R | 37 | 8 | 0 | 1 | 1 | 3.38 | .273 | 1.13 | 5.6 | 4.5 | 9.0 | 8.0 | 5 | 3 | 3 | 1 | 4 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.13 |