| SP | Yamamoto, Y.Yamamoto, Yoshinobu † >> | 26 | 2025 | R | 96 | 30 | 30 | 21 | 6 | 2.97 | .277 | 1.12 | 7.0 | 3.1 | 10.1 | 187.2 | 146 | 66 | 62 | 15 | 65 | 209 | 0 | 0 | 0 | 0 | 18 | 5 | 2 | 2.93 |
| SP | Rogers, T.Rogers, Trevor † $ >> | 27 | 2025 | L | 96 | 30 | 30 | 18 | 4 | 2.98 | .265 | 1.06 | 7.1 | 2.4 | 8.5 | 202.1 | 160 | 72 | 67 | 18 | 54 | 191 | 1 | 0 | 0 | 1 | 25 | 5 | 0 | 3.14 |
| SP | deGrom, J.deGrom, Jacob # $ >> | 37 | 2025 | R | 98 | 29 | 29 | 11 | 9 | 4.90 | .333 | 1.47 | 10.3 | 3.0 | 9.1 | 161.2 | 185 | 92 | 88 | 22 | 53 | 162 | 0 | 0 | 0 | 0 | 11 | 4 | 2 | 3.83 |
| SP | Cameron, N.Cameron, Noah † >> | 25 | 2025 | L | 80 | 28 | 28 | 14 | 7 | 4.73 | .333 | 1.46 | 8.9 | 4.2 | 8.6 | 152.1 | 151 | 81 | 80 | 33 | 71 | 145 | 0 | 0 | 0 | 0 | 9 | 6 | 5 | 5.43 |
| SP | Williams, G.Williams, Gavin # >> | 25 | 2025 | R | 68 | 28 | 28 | 14 | 3 | 4.10 | .312 | 1.34 | 7.6 | 4.4 | 8.6 | 158.0 | 134 | 72 | 72 | 16 | 77 | 151 | 1 | 0 | 0 | 1 | 13 | 4 | 5 | 3.94 |
| RP | Svanson, M.Svanson, Matt >> | 26 | 2025 | R | 98 | 80 | 0 | 6 | 4 | 2.99 | .272 | 1.10 | 5.4 | 4.5 | 9.2 | 111.1 | 67 | 38 | 37 | 10 | 56 | 114 | 0 | 5 | 2 | 0 | 0 | 2 | 3 | 3.68 |
| RP | Thielbar, C.Thielbar, Caleb >> | 38 | 2025 | L | 91 | 101 | 0 | 4 | 2 | 2.43 | .264 | 1.07 | 7.3 | 2.3 | 8.4 | 85.1 | 69 | 24 | 23 | 5 | 22 | 79 | 0 | 6 | 3 | 0 | 0 | 1 | 0 | 2.72 |
| RP | Bautista, F.Bautista, Félix >> | 30 | 2025 | R | 84 | 72 | 0 | 5 | 5 | 3.12 | .295 | 1.25 | 5.5 | 5.8 | 12.6 | 75.0 | 46 | 26 | 26 | 4 | 48 | 105 | 0 | 12 | 3 | 0 | 0 | 0 | 2 | 2.81 |
| RP | Hoffman, J.Hoffman, Jeff >> | 32 | 2025 | R | 57 | 30 | 0 | 2 | 1 | 6.61 | .277 | 1.15 | 7.0 | 3.5 | 10.5 | 31.1 | 24 | 23 | 23 | 5 | 12 | 36 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.94 |