| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 27 | 27 | 7 | 14 | 4.27 | .279 | 1.14 | 8.2 | 2.1 | 5.9 | 213.0 | 193 | 111 | 101 | 27 | 49 | 139 | 6 | 0 | 0 | 2 | 12 | 5 | 3 | 4.10 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 27 | 27 | 11 | 12 | 4.32 | .302 | 1.29 | 8.6 | 3.0 | 6.9 | 193.2 | 185 | 105 | 93 | 22 | 64 | 147 | 4 | 0 | 0 | 1 | 18 | 2 | 3 | 3.98 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 26 | 26 | 7 | 18 | 5.33 | .321 | 1.40 | 10.1 | 2.5 | 4.9 | 190.2 | 214 | 130 | 113 | 30 | 52 | 103 | 14 | 0 | 0 | 2 | 8 | 5 | 3 | 4.87 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 26 | 26 | 7 | 14 | 4.77 | .319 | 1.39 | 9.7 | 2.9 | 4.4 | 188.2 | 202 | 109 | 100 | 25 | 61 | 91 | 6 | 0 | 0 | 0 | 12 | 2 | 6 | 4.77 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 73 | 25 | 25 | 7 | 15 | 5.12 | .342 | 1.53 | 10.2 | 3.6 | 4.3 | 175.2 | 199 | 110 | 100 | 28 | 70 | 84 | 8 | 0 | 0 | 2 | 10 | 5 | 2 | 5.41 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 67 | 0 | 2 | 2 | 2.61 | .267 | 1.07 | 5.7 | 4.0 | 9.5 | 58.2 | 37 | 17 | 17 | 7 | 26 | 61 | 0 | 5 | 1 | 0 | 0 | 1 | 2 | 3.86 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 61 | 0 | 1 | 0 | 2.12 | .255 | 1.01 | 6.8 | 2.3 | 6.7 | 46.2 | 35 | 11 | 11 | 2 | 12 | 34 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 2.93 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 22 | 0 | 0 | 2 | 1.90 | .211 | 0.80 | 5.5 | 2.0 | 5.1 | 23.2 | 14 | 7 | 5 | 3 | 5 | 13 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 4.22 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 41 | 0 | 0 | 0 | 1.69 | .279 | 1.16 | 4.8 | 5.9 | 9.3 | 26.2 | 14 | 5 | 5 | 1 | 17 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.38 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 19 | 0 | 0 | 0 | 2.92 | .327 | 1.42 | 7.1 | 6.0 | 4.9 | 24.2 | 19 | 9 | 8 | 4 | 16 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.21 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 7 | 0 | 2 | 4 | 6.10 | .415 | 2.13 | 14.4 | 5.4 | 8.1 | 10.1 | 16 | 7 | 7 | 1 | 6 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.30 |