| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 29 | 29 | 10 | 5 | 3.91 | .297 | 1.26 | 7.8 | 3.6 | 8.0 | 182.0 | 158 | 83 | 79 | 25 | 72 | 161 | 2 | 0 | 0 | 1 | 17 | 1 | 4 | 4.22 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 28 | 28 | 7 | 14 | 5.97 | .336 | 1.48 | 9.7 | 3.6 | 4.3 | 164.1 | 177 | 111 | 109 | 20 | 66 | 79 | 6 | 0 | 0 | 0 | 9 | 6 | 1 | 4.94 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 28 | 28 | 9 | 14 | 5.56 | .326 | 1.43 | 10.6 | 2.3 | 4.6 | 142.1 | 167 | 96 | 88 | 25 | 37 | 72 | 0 | 0 | 0 | 0 | 10 | 3 | 3 | 5.12 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 81 | 0 | 6 | 0 | 2.67 | .261 | 1.05 | 7.3 | 2.1 | 9.9 | 81.0 | 66 | 24 | 24 | 13 | 19 | 89 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 3.63 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 70 | 0 | 5 | 5 | 2.77 | .267 | 1.03 | 6.1 | 3.2 | 8.3 | 65.0 | 44 | 20 | 20 | 3 | 23 | 60 | 0 | 5 | 1 | 0 | 0 | 4 | 3 | 3.00 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 81 | 0 | 3 | 0 | 3.22 | .303 | 1.29 | 7.7 | 3.9 | 9.3 | 64.1 | 55 | 24 | 23 | 8 | 28 | 66 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.92 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 55 | 0 | 2 | 2 | 3.21 | .273 | 1.13 | 7.4 | 2.7 | 7.9 | 56.0 | 46 | 23 | 20 | 10 | 17 | 49 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 4.48 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 19 | 0 | 5 | 3 | 1.42 | .240 | 0.88 | 4.9 | 3.2 | 6.4 | 31.2 | 17 | 9 | 5 | 3 | 11 | 22 | 0 | 3 | 0 | 0 | 0 | 2 | 1 | 4.10 |