| SP | Johnson, W.Johnson, Walter † >> | 26 | 1913 | R | 95 | 27 | 27 | 11 | 8 | 3.26 | .272 | 1.10 | 7.9 | 2.1 | 5.3 | 179.2 | 157 | 75 | 65 | 19 | 41 | 106 | 7 | 0 | 0 | 3 | 18 | 3 | 4 | 3.93 |
| SP | Snell, B.Snell, Blake $ >> | 25 | 2018 | L | 80 | 26 | 26 | 8 | 8 | 4.73 | .324 | 1.41 | 8.4 | 4.3 | 7.3 | 142.2 | 133 | 78 | 75 | 11 | 68 | 115 | 1 | 0 | 0 | 1 | 14 | 4 | 11 | 3.91 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 49 | 26 | 25 | 18 | 5 | 2.25 | .276 | 1.14 | 6.4 | 3.8 | 6.8 | 179.2 | 128 | 49 | 45 | 11 | 76 | 135 | 2 | 0 | 0 | 0 | 22 | 1 | 7 | 3.58 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 76 | 0 | 1 | 1 | 3.15 | .320 | 1.40 | 9.0 | 3.6 | 8.5 | 74.1 | 74 | 27 | 26 | 10 | 30 | 70 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 4.12 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 80 | 0 | 0 | 2 | 3.16 | .326 | 1.43 | 8.2 | 4.8 | 7.0 | 68.1 | 62 | 28 | 24 | 4 | 36 | 53 | 0 | 3 | 2 | 0 | 0 | 1 | 4 | 3.84 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 62 | 0 | 5 | 3 | 3.23 | .292 | 1.22 | 9.0 | 2.1 | 7.9 | 55.2 | 55 | 20 | 20 | 6 | 13 | 48 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.44 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 56 | 0 | 4 | 2 | 2.54 | .255 | 1.03 | 6.1 | 3.3 | 7.9 | 49.2 | 33 | 14 | 14 | 4 | 18 | 43 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 3.41 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 26 | 0 | 1 | 3 | 4.28 | .289 | 1.19 | 7.4 | 3.5 | 9.0 | 33.2 | 27 | 16 | 16 | 7 | 13 | 33 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 5.03 |