| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 11 | 11 | 2 | 1 | 3.19 | .326 | 1.43 | 9.3 | 3.7 | 4.8 | 53.2 | 55 | 22 | 19 | 6 | 22 | 28 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 4.72 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 11 | 11 | 7 | 3 | 2.67 | .257 | 1.02 | 5.4 | 3.9 | 4.8 | 67.1 | 40 | 23 | 20 | 3 | 29 | 36 | 1 | 0 | 0 | 1 | 6 | 1 | 1 | 3.85 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 11 | 11 | 6 | 0 | 2.39 | .296 | 1.24 | 6.8 | 4.5 | 9.0 | 60.1 | 45 | 17 | 16 | 5 | 30 | 60 | 0 | 0 | 0 | 0 | 7 | 1 | 0 | 3.63 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 61 | 11 | 11 | 5 | 3 | 6.29 | .333 | 1.46 | 9.0 | 4.3 | 6.6 | 48.2 | 48 | 34 | 34 | 7 | 23 | 35 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 5.00 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 30 | 0 | 5 | 2 | 2.78 | .287 | 1.18 | 6.4 | 4.4 | 6.4 | 35.2 | 25 | 12 | 11 | 1 | 17 | 25 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.49 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 32 | 0 | 3 | 0 | 5.04 | .342 | 1.48 | 7.9 | 5.4 | 7.2 | 25.0 | 22 | 15 | 14 | 3 | 15 | 20 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 5.00 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 31 | 0 | 1 | 1 | 4.86 | .281 | 1.14 | 6.8 | 3.5 | 7.6 | 33.1 | 25 | 18 | 18 | 4 | 13 | 28 | 0 | 7 | 1 | 0 | 0 | 1 | 0 | 4.15 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 20 | 0 | 2 | 0 | 2.70 | .302 | 1.25 | 8.1 | 3.2 | 3.6 | 20.0 | 18 | 6 | 6 | 2 | 7 | 8 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 4.70 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 33 | 0 | 1 | 1 | 3.58 | .252 | 1.01 | 4.7 | 4.7 | 8.3 | 27.2 | 14 | 11 | 11 | 4 | 14 | 25 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.63 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 16 | 0 | 0 | 2 | 1.73 | .243 | 0.96 | 5.5 | 3.1 | 6.6 | 26.0 | 16 | 6 | 5 | 3 | 9 | 19 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 4.08 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 23 | 0 | 4 | 0 | 3.00 | .308 | 1.33 | 6.4 | 5.6 | 6.9 | 21.0 | 15 | 7 | 7 | 2 | 13 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.57 |