| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 11 | 11 | 5 | 5 | 3.51 | .277 | 1.10 | 7.6 | 2.4 | 5.6 | 89.2 | 75 | 36 | 35 | 6 | 24 | 55 | 4 | 0 | 0 | 1 | 8 | 4 | 2 | 3.58 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 11 | 11 | 7 | 2 | 2.36 | .290 | 1.23 | 7.5 | 3.5 | 7.2 | 80.0 | 67 | 24 | 21 | 5 | 31 | 64 | 1 | 0 | 0 | 1 | 9 | 0 | 2 | 3.38 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 11 | 11 | 4 | 5 | 4.17 | .305 | 1.32 | 8.6 | 3.3 | 5.6 | 69.0 | 66 | 35 | 32 | 12 | 25 | 43 | 1 | 0 | 0 | 1 | 6 | 0 | 1 | 5.10 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 11 | 11 | 2 | 7 | 8.58 | .399 | 1.98 | 13.2 | 4.8 | 6.8 | 56.2 | 82 | 54 | 54 | 15 | 30 | 42 | 2 | 0 | 0 | 0 | 2 | 1 | 1 | 6.64 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 32 | 0 | 2 | 1 | 2.68 | .234 | 0.92 | 5.0 | 3.4 | 8.3 | 40.1 | 22 | 12 | 12 | 3 | 15 | 37 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 3.25 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 24 | 0 | 1 | 0 | 1.17 | .240 | 0.95 | 4.2 | 4.5 | 10.2 | 30.2 | 14 | 4 | 4 | 1 | 15 | 34 | 0 | 6 | 0 | 0 | 0 | 0 | 2 | 2.67 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 93 | 15 | 0 | 0 | 0 | 6.35 | .311 | 1.29 | 7.4 | 4.2 | 6.9 | 17.0 | 14 | 12 | 12 | 0 | 8 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.06 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 8 | 0 | 1 | 1 | 5.63 | .385 | 1.88 | 11.3 | 5.6 | 11.3 | 8.0 | 10 | 5 | 5 | 0 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.38 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 7 | 0 | 0 | 0 | 1.08 | .242 | 0.96 | 5.6 | 3.4 | 9.0 | 8.1 | 5 | 1 | 1 | 1 | 3 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 6 | 0 | 0 | 0 | 2.16 | .242 | 0.96 | 5.6 | 3.4 | 4.5 | 8.1 | 5 | 2 | 2 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.13 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 3 | 0 | 1 | 1 | 7.71 | .417 | 2.14 | 13.5 | 9.0 | 4.5 | 2.1 | 3 | 2 | 2 | 1 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 11.50 |