| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 98 | 15 | 15 | 6 | 8 | 4.17 | .324 | 1.41 | 8.8 | 3.9 | 9.5 | 99.1 | 97 | 49 | 46 | 10 | 43 | 105 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 3.59 |
| SP | Buchholz, C.Buchholz, Clay # >> | 29 | 2013 | R | 81 | 15 | 15 | 7 | 6 | 3.97 | .289 | 1.20 | 8.7 | 2.2 | 8.7 | 106.2 | 102 | 51 | 47 | 10 | 26 | 102 | 2 | 0 | 0 | 1 | 8 | 2 | 2 | 3.09 |
| SP | Shields, J.Shields, James >> | 30 | 2011 | R | 63 | 15 | 15 | 6 | 6 | 6.90 | .411 | 2.07 | 12.1 | 6.6 | 7.9 | 91.1 | 122 | 72 | 70 | 23 | 67 | 80 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 6.80 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 57 | 15 | 15 | 5 | 5 | 5.78 | .362 | 1.66 | 10.5 | 4.5 | 8.9 | 90.1 | 105 | 61 | 58 | 12 | 45 | 89 | 1 | 0 | 0 | 0 | 8 | 4 | 5 | 4.39 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 27 | 2012 | L | 48 | 15 | 15 | 7 | 3 | 4.58 | .321 | 1.41 | 9.2 | 3.5 | 9.9 | 94.1 | 96 | 49 | 48 | 13 | 37 | 103 | 0 | 0 | 0 | 0 | 8 | 1 | 6 | 3.82 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 39 | 0 | 4 | 0 | 2.25 | .291 | 1.19 | 8.3 | 2.4 | 10.4 | 52.0 | 48 | 15 | 13 | 5 | 14 | 60 | 0 | 5 | 1 | 0 | 0 | 2 | 0 | 2.87 |
| RP | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 81 | 37 | 0 | 2 | 1 | 3.68 | .327 | 1.45 | 7.6 | 5.5 | 11.0 | 44.0 | 37 | 18 | 18 | 5 | 27 | 54 | 0 | 7 | 1 | 0 | 0 | 0 | 1 | 3.86 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 60 | 28 | 0 | 3 | 2 | 2.79 | .346 | 1.52 | 9.3 | 4.3 | 10.6 | 29.0 | 30 | 11 | 9 | 3 | 14 | 34 | 0 | 5 | 3 | 0 | 0 | 2 | 0 | 3.66 |
| RP | Devenski, C.Devenski, Chris >> | 26 | 2017 | R | 49 | 21 | 0 | 0 | 1 | 1.38 | .271 | 1.08 | 6.6 | 3.1 | 12.8 | 26.0 | 19 | 6 | 4 | 1 | 9 | 37 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1.81 |
| SP | Romero, R.Romero, Ricky >> | 26 | 2011 | L | 38 | 8 | 0 | 1 | 2 | 2.92 | .229 | 0.89 | 6.8 | 1.5 | 5.3 | 12.1 | 9 | 4 | 4 | 3 | 2 | 7 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.58 |