| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 99 | 32 | 31 | 13 | 12 | 4.21 | .300 | 1.26 | 7.7 | 3.6 | 9.7 | 205.0 | 176 | 100 | 96 | 32 | 83 | 221 | 2 | 0 | 0 | 0 | 19 | 4 | 6 | 4.15 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 84 | 33 | 33 | 14 | 13 | 4.51 | .316 | 1.37 | 9.9 | 2.5 | 9.2 | 221.2 | 242 | 117 | 111 | 30 | 62 | 225 | 2 | 0 | 0 | 0 | 17 | 3 | 9 | 3.61 |
| SP | Keuchel, D.Keuchel, Dallas # >> | 27 | 2015 | L | 68 | 32 | 31 | 14 | 10 | 4.77 | .322 | 1.40 | 10.1 | 2.5 | 7.6 | 205.2 | 230 | 110 | 109 | 36 | 57 | 174 | 2 | 0 | 0 | 0 | 16 | 6 | 3 | 4.51 |
| SP | Wainwright, A.Wainwright, Adam # >> | 29 | 2010 | R | 55 | 31 | 31 | 9 | 9 | 5.07 | .315 | 1.34 | 9.5 | 2.6 | 7.4 | 190.0 | 201 | 109 | 107 | 42 | 54 | 157 | 1 | 0 | 0 | 0 | 14 | 7 | 4 | 5.18 |
| SP | Bumgarner, M.Bumgarner, Madison # >> | 26 | 2016 | L | 76 | 34 | 33 | 8 | 16 | 6.25 | .341 | 1.54 | 10.6 | 3.3 | 9.3 | 184.1 | 216 | 132 | 128 | 35 | 67 | 190 | 3 | 0 | 0 | 0 | 13 | 3 | 4 | 4.55 |
| SU | Robertson, D.Robertson, David >> | 32 | 2017 | R | 85 | 60 | 0 | 2 | 2 | 3.34 | .298 | 1.24 | 7.1 | 4.1 | 9.0 | 62.0 | 49 | 23 | 23 | 7 | 28 | 62 | 0 | 2 | 2 | 0 | 0 | 2 | 6 | 3.92 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 32 | 0 | 3 | 3 | 4.01 | .289 | 1.19 | 8.2 | 2.7 | 11.7 | 33.2 | 30 | 15 | 15 | 4 | 10 | 43 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 2.97 |
| RP | Frieri, E.Frieri, Ernesto >> | 26 | 2012 | R | 67 | 34 | 0 | 0 | 3 | 4.29 | .344 | 1.54 | 10.5 | 3.6 | 12.3 | 35.2 | 41 | 17 | 17 | 6 | 14 | 48 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.77 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 46 | 0 | 4 | 1 | 4.66 | .280 | 1.14 | 8.0 | 2.3 | 9.4 | 46.1 | 41 | 25 | 24 | 14 | 12 | 48 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 5.72 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 94 | 44 | 0 | 1 | 2 | 5.71 | .305 | 1.27 | 9.2 | 2.2 | 11.6 | 41.0 | 42 | 26 | 26 | 11 | 10 | 53 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 4.78 |
| RP | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 66 | 6 | 0 | 0 | 0 | 6.35 | .261 | 1.06 | 5.4 | 5.4 | 12.6 | 5.2 | 3 | 4 | 4 | 2 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.20 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 82 | 24 | 3 | 2 | 4 | 5.97 | .343 | 1.55 | 9.7 | 4.2 | 6.9 | 110.0 | 119 | 76 | 73 | 31 | 51 | 84 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 6.58 |