| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 98 | 38 | 38 | 16 | 10 | 3.98 | .286 | 1.19 | 8.9 | 1.8 | 9.9 | 258.0 | 255 | 118 | 114 | 28 | 51 | 285 | 7 | 0 | 0 | 1 | 21 | 4 | 6 | 2.84 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 37 | 37 | 13 | 8 | 3.95 | .291 | 1.21 | 7.9 | 3.0 | 9.6 | 228.0 | 200 | 101 | 100 | 31 | 76 | 242 | 4 | 0 | 0 | 2 | 20 | 5 | 6 | 3.71 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 75 | 34 | 34 | 12 | 11 | 5.78 | .341 | 1.53 | 10.0 | 3.8 | 7.5 | 185.1 | 205 | 121 | 119 | 37 | 78 | 155 | 0 | 0 | 0 | 0 | 17 | 5 | 10 | 5.27 |
| SP | Oswalt, R.Oswalt, Roy # >> | 33 | 2010 | R | 67 | 31 | 31 | 7 | 11 | 6.07 | .348 | 1.58 | 10.7 | 3.6 | 6.8 | 167.2 | 199 | 120 | 113 | 30 | 66 | 126 | 0 | 0 | 0 | 0 | 12 | 4 | 2 | 5.08 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 86 | 92 | 0 | 13 | 5 | 4.49 | .308 | 1.33 | 8.1 | 3.9 | 10.3 | 114.1 | 102 | 57 | 57 | 14 | 50 | 131 | 0 | 2 | 3 | 0 | 0 | 1 | 2 | 3.64 |
| RP | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 82 | 81 | 0 | 6 | 4 | 4.86 | .324 | 1.44 | 8.0 | 5.0 | 11.0 | 87.0 | 77 | 48 | 47 | 12 | 48 | 106 | 0 | 0 | 6 | 0 | 0 | 0 | 2 | 4.01 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 74 | 64 | 0 | 4 | 3 | 3.66 | .282 | 1.15 | 7.5 | 2.9 | 9.6 | 71.1 | 59 | 29 | 29 | 7 | 23 | 76 | 0 | 3 | 3 | 0 | 0 | 2 | 5 | 3.20 |
| RP | Feliz, N.Feliz, Neftali >> | 22 | 2010 | R | 64 | 50 | 0 | 3 | 2 | 3.75 | .311 | 1.33 | 8.8 | 3.2 | 9.2 | 50.1 | 49 | 23 | 21 | 8 | 18 | 51 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.18 |
| SP | Morton, C.Morton, Charlie >> | 36 | 2019 | R | 54 | 18 | 0 | 5 | 2 | 3.77 | .295 | 1.23 | 8.6 | 2.5 | 8.9 | 76.1 | 73 | 34 | 32 | 16 | 21 | 75 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 4.67 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 80 | 0 | 5 | 14 | 3.96 | .256 | 1.02 | 7.4 | 1.9 | 12.0 | 77.1 | 63 | 35 | 34 | 14 | 16 | 103 | 0 | 43 | 4 | 0 | 0 | 1 | 4 | 3.35 |