| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 34 | 34 | 7 | 16 | 5.84 | .333 | 1.47 | 10.4 | 2.8 | 8.9 | 151.0 | 175 | 106 | 98 | 27 | 47 | 149 | 0 | 0 | 0 | 0 | 4 | 4 | 7 | 4.36 |
| SP | Bedard, E.Bedard, Erik >> | 28 | 2007 | L | 80 | 33 | 33 | 11 | 17 | 5.20 | .353 | 1.59 | 9.9 | 4.5 | 10.0 | 200.2 | 221 | 122 | 116 | 30 | 99 | 223 | 0 | 0 | 0 | 0 | 18 | 8 | 2 | 4.33 |
| SP | Moyer, J.Moyer, Jamie # >> | 40 | 2002 | L | 61 | 32 | 32 | 9 | 13 | 5.37 | .323 | 1.40 | 10.1 | 2.5 | 6.6 | 191.0 | 214 | 115 | 114 | 27 | 53 | 141 | 0 | 0 | 0 | 0 | 12 | 6 | 3 | 4.29 |
| SP | Burkett, J.Burkett, John # >> | 37 | 2001 | R | 49 | 32 | 32 | 8 | 15 | 6.46 | .353 | 1.61 | 9.8 | 4.6 | 7.5 | 192.1 | 210 | 138 | 138 | 44 | 99 | 159 | 1 | 0 | 0 | 1 | 12 | 6 | 8 | 5.96 |
| SP | Johnson, J.Johnson, Josh >> | 25 | 2009 | R | 46 | 31 | 31 | 5 | 16 | 5.74 | .351 | 1.60 | 10.5 | 3.9 | 7.1 | 188.0 | 220 | 126 | 120 | 34 | 81 | 148 | 0 | 0 | 0 | 0 | 14 | 4 | 9 | 5.13 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 87 | 0 | 6 | 3 | 2.85 | .254 | 1.00 | 7.4 | 1.6 | 9.6 | 142.0 | 117 | 46 | 45 | 13 | 25 | 152 | 0 | 5 | 5 | 0 | 0 | 3 | 2 | 2.64 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 84 | 0 | 7 | 7 | 3.91 | .298 | 1.26 | 7.5 | 3.9 | 9.0 | 103.2 | 86 | 45 | 45 | 14 | 45 | 103 | 0 | 6 | 4 | 0 | 0 | 1 | 2 | 4.11 |
| RP | Cormier, R.Cormier, Rheal >> | 36 | 2003 | L | 62 | 85 | 0 | 5 | 3 | 2.60 | .271 | 1.12 | 7.0 | 3.1 | 7.3 | 107.1 | 83 | 32 | 31 | 14 | 37 | 87 | 0 | 9 | 3 | 0 | 0 | 0 | 0 | 4.11 |
| RP | Aardsma, D.Aardsma, David >> | 28 | 2009 | R | 36 | 44 | 0 | 3 | 0 | 3.06 | .296 | 1.20 | 7.4 | 3.4 | 10.1 | 50.0 | 41 | 17 | 17 | 7 | 19 | 56 | 0 | 1 | 0 | 0 | 0 | 3 | 1 | 3.90 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 36 | 18 | 0 | 0 | 1 | 5.04 | .324 | 1.40 | 7.6 | 5.0 | 6.1 | 25.0 | 21 | 14 | 14 | 5 | 14 | 17 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 6.04 |