| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 96 | 34 | 34 | 14 | 11 | 3.94 | .313 | 1.34 | 8.6 | 3.5 | 6.8 | 237.2 | 226 | 108 | 104 | 23 | 92 | 178 | 3 | 0 | 0 | 0 | 20 | 7 | 5 | 4.01 |
| SP | Vazquez, J.Vazquez, Javier # >> | 33 | 2009 | R | 86 | 33 | 33 | 13 | 14 | 4.89 | .304 | 1.28 | 9.1 | 2.4 | 8.0 | 213.1 | 216 | 118 | 116 | 36 | 57 | 189 | 2 | 0 | 0 | 0 | 16 | 7 | 3 | 4.32 |
| SP | Pettitte, A.Pettitte, Andy # >> | 33 | 2005 | L | 78 | 32 | 32 | 11 | 14 | 5.63 | .315 | 1.34 | 9.7 | 2.3 | 6.6 | 192.0 | 207 | 120 | 120 | 37 | 50 | 140 | 0 | 0 | 0 | 0 | 13 | 8 | 3 | 4.95 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 32 | 32 | 8 | 15 | 6.32 | .369 | 1.72 | 10.4 | 5.1 | 7.1 | 162.1 | 188 | 120 | 114 | 33 | 91 | 127 | 0 | 0 | 0 | 0 | 9 | 6 | 6 | 5.88 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 31 | 31 | 13 | 14 | 5.61 | .336 | 1.48 | 9.5 | 3.8 | 6.7 | 184.1 | 195 | 120 | 115 | 34 | 78 | 137 | 2 | 0 | 0 | 1 | 12 | 7 | 6 | 5.30 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 89 | 0 | 3 | 5 | 3.47 | .267 | 1.02 | 7.8 | 1.4 | 8.8 | 127.0 | 110 | 51 | 49 | 16 | 20 | 124 | 0 | 10 | 3 | 0 | 0 | 9 | 2 | 3.37 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 81 | 0 | 5 | 4 | 4.61 | .319 | 1.37 | 9.0 | 3.5 | 10.2 | 99.2 | 99 | 54 | 51 | 16 | 38 | 112 | 0 | 13 | 3 | 0 | 0 | 3 | 0 | 4.08 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 56 | 0 | 7 | 4 | 5.57 | .340 | 1.48 | 8.3 | 5.2 | 9.8 | 64.2 | 59 | 43 | 40 | 6 | 37 | 70 | 0 | 2 | 1 | 0 | 0 | 4 | 2 | 3.95 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 44 | 53 | 0 | 2 | 1 | 4.75 | .289 | 1.22 | 7.2 | 3.9 | 9.2 | 60.2 | 48 | 36 | 32 | 9 | 26 | 61 | 0 | 3 | 3 | 0 | 0 | 0 | 4 | 4.22 |
| RP | Manzanillo, J.Manzanillo, Josias >> | 34 | 2001 | R | 32 | 43 | 0 | 1 | 1 | 4.75 | .346 | 1.52 | 7.9 | 5.9 | 7.9 | 47.1 | 41 | 29 | 25 | 7 | 31 | 41 | 0 | 4 | 1 | 0 | 0 | 3 | 1 | 5.36 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 35 | 1 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 9.0 | 0.0 | 0.0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |