| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 96 | 6 | 6 | 4 | 1 | 2.68 | .277 | 1.13 | 6.9 | 3.3 | 6.7 | 47.0 | 36 | 14 | 14 | 5 | 17 | 35 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 4.04 |
| SP | Vazquez, J.Vazquez, Javier # >> | 33 | 2009 | R | 86 | 6 | 6 | 1 | 4 | 5.86 | .312 | 1.30 | 10.0 | 1.8 | 9.0 | 35.1 | 39 | 25 | 23 | 8 | 7 | 35 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.74 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 6 | 6 | 3 | 2 | 3.93 | .321 | 1.42 | 10.0 | 3.0 | 6.3 | 36.2 | 40 | 16 | 16 | 3 | 12 | 25 | 0 | 0 | 0 | 0 | 4 | 0 | 2 | 3.69 |
| SP | Zambrano, C.Zambrano, Carlos >> | 24 | 2005 | R | 70 | 6 | 6 | 4 | 2 | 6.21 | .379 | 1.83 | 10.6 | 5.9 | 7.1 | 29.0 | 34 | 20 | 20 | 5 | 19 | 23 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 5.62 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 6 | 6 | 1 | 5 | 6.51 | .367 | 1.74 | 12.4 | 3.4 | 6.1 | 37.1 | 51 | 28 | 27 | 8 | 14 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.59 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 18 | 0 | 0 | 1 | 2.30 | .188 | 0.70 | 5.7 | 0.7 | 8.7 | 27.1 | 17 | 7 | 7 | 4 | 2 | 26 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.22 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 13 | 0 | 0 | 2 | 7.90 | .388 | 1.90 | 14.5 | 3.5 | 13.2 | 13.2 | 21 | 12 | 12 | 1 | 5 | 19 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 2.23 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 55 | 9 | 0 | 0 | 0 | 3.38 | .347 | 1.50 | 9.9 | 4.5 | 8.1 | 10.2 | 11 | 4 | 4 | 0 | 5 | 9 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.00 |
| RP | Urbina, U.Urbina, Ugueth >> | 28 | 2002 | R | 44 | 10 | 0 | 0 | 0 | 2.19 | .178 | 0.65 | 4.5 | 1.5 | 6.8 | 12.1 | 6 | 3 | 3 | 0 | 2 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Manzanillo, J.Manzanillo, Josias >> | 34 | 2001 | R | 32 | 7 | 0 | 0 | 0 | 5.63 | .400 | 2.00 | 6.8 | 11.3 | 7.9 | 8.0 | 6 | 5 | 5 | 1 | 10 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.63 |
| SP | Jimenez, U.Jimenez, Ubaldo | 25 | 2009 | R | 35 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |