| SP | Johnson, R.Johnson, Randy † >> | 38 | 2001 | L | 97 | 33 | 33 | 13 | 14 | 3.07 | .282 | 1.13 | 7.7 | 2.5 | 9.9 | 237.1 | 202 | 87 | 81 | 24 | 67 | 260 | 8 | 0 | 0 | 0 | 22 | 10 | 6 | 3.10 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 87 | 32 | 32 | 13 | 11 | 3.77 | .284 | 1.15 | 8.3 | 2.1 | 7.1 | 231.2 | 213 | 101 | 97 | 22 | 53 | 183 | 11 | 0 | 0 | 1 | 18 | 9 | 2 | 3.46 |
| SP | Carpenter, C.Carpenter, Chris >> | 34 | 2009 | R | 80 | 32 | 32 | 16 | 6 | 4.28 | .310 | 1.31 | 9.0 | 2.7 | 6.2 | 208.0 | 209 | 102 | 99 | 21 | 63 | 144 | 2 | 0 | 0 | 0 | 16 | 8 | 1 | 3.95 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 31 | 31 | 8 | 10 | 5.66 | .328 | 1.42 | 9.9 | 2.9 | 7.3 | 160.2 | 176 | 104 | 101 | 27 | 52 | 130 | 0 | 0 | 0 | 0 | 14 | 7 | 0 | 4.68 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 100 | 84 | 0 | 5 | 4 | 3.51 | .272 | 1.09 | 6.8 | 3.1 | 10.0 | 112.2 | 84 | 47 | 44 | 15 | 39 | 124 | 0 | 8 | 6 | 0 | 0 | 3 | 0 | 3.65 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 71 | 0 | 5 | 6 | 4.75 | .323 | 1.40 | 7.3 | 5.2 | 8.4 | 91.0 | 74 | 50 | 48 | 14 | 53 | 85 | 0 | 6 | 6 | 0 | 0 | 3 | 1 | 4.98 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 79 | 61 | 0 | 9 | 5 | 3.84 | .308 | 1.29 | 6.9 | 4.9 | 9.8 | 72.2 | 55 | 31 | 31 | 11 | 39 | 78 | 0 | 9 | 2 | 0 | 0 | 3 | 0 | 4.57 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 69 | 38 | 0 | 2 | 1 | 2.86 | .267 | 0.99 | 6.8 | 2.2 | 8.8 | 50.1 | 38 | 16 | 16 | 6 | 12 | 49 | 0 | 3 | 2 | 0 | 0 | 5 | 0 | 3.62 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 86 | 30 | 0 | 0 | 1 | 4.45 | .312 | 1.33 | 7.6 | 4.5 | 10.1 | 32.1 | 27 | 16 | 16 | 2 | 16 | 36 | 0 | 2 | 0 | 0 | 0 | 1 | 4 | 3.16 |
| SP | Greinke, Z.Greinke, Zack >> | 26 | 2009 | R | 77 | 3 | 0 | 0 | 0 | 12.00 | .438 | 2.33 | 21.0 | 0.0 | 6.0 | 3.0 | 7 | 4 | 4 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.67 |