| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 33 | 33 | 13 | 13 | 3.62 | .324 | 1.41 | 8.1 | 4.7 | 9.2 | 193.2 | 173 | 91 | 78 | 19 | 101 | 197 | 0 | 0 | 0 | 0 | 17 | 4 | 2 | 3.87 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 72 | 32 | 32 | 7 | 12 | 7.00 | .366 | 1.70 | 12.1 | 3.3 | 7.3 | 173.2 | 232 | 141 | 135 | 48 | 63 | 141 | 0 | 0 | 0 | 0 | 7 | 6 | 0 | 6.17 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 84 | 32 | 32 | 14 | 9 | 4.44 | .321 | 1.38 | 9.3 | 3.2 | 6.8 | 208.2 | 216 | 109 | 103 | 31 | 73 | 157 | 1 | 0 | 0 | 0 | 18 | 7 | 5 | 4.58 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 68 | 32 | 32 | 12 | 9 | 6.74 | .346 | 1.55 | 10.6 | 3.4 | 6.0 | 163.0 | 192 | 127 | 122 | 40 | 61 | 109 | 1 | 0 | 0 | 0 | 14 | 6 | 3 | 6.09 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 58 | 31 | 30 | 10 | 12 | 6.91 | .358 | 1.64 | 12.3 | 2.5 | 6.0 | 183.2 | 250 | 148 | 141 | 43 | 51 | 122 | 3 | 0 | 0 | 0 | 6 | 6 | 3 | 5.66 |
| RP | Lidge, B.Lidge, Brad † >> | 28 | 2004 | R | 82 | 83 | 0 | 10 | 2 | 2.57 | .262 | 1.03 | 6.0 | 3.3 | 10.2 | 119.0 | 79 | 39 | 34 | 12 | 43 | 135 | 0 | 8 | 3 | 0 | 0 | 5 | 3 | 3.25 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 57 | 0 | 6 | 3 | 2.34 | .275 | 1.14 | 6.0 | 4.3 | 9.9 | 61.2 | 41 | 18 | 16 | 5 | 29 | 67 | 0 | 12 | 0 | 0 | 0 | 0 | 1 | 3.30 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 39 | 0 | 6 | 1 | 5.17 | .316 | 1.32 | 9.8 | 2.1 | 8.4 | 47.0 | 51 | 29 | 27 | 12 | 11 | 44 | 0 | 1 | 4 | 0 | 0 | 3 | 0 | 5.34 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 43 | 0 | 0 | 2 | 5.47 | .313 | 1.37 | 9.7 | 2.8 | 7.4 | 52.2 | 56 | 32 | 32 | 12 | 16 | 43 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 5.27 |