| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 99 | 7 | 7 | 4 | 2 | 1.57 | .262 | 1.03 | 6.7 | 2.6 | 9.4 | 51.2 | 38 | 10 | 9 | 1 | 15 | 53 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 2.18 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 82 | 7 | 7 | 4 | 2 | 4.78 | .337 | 1.48 | 9.6 | 3.8 | 8.2 | 43.1 | 46 | 24 | 23 | 6 | 18 | 39 | 0 | 0 | 0 | 0 | 4 | 2 | 4 | 4.40 |
| SP | Richards, G.Richards, Garrett # >> | 26 | 2014 | R | 72 | 6 | 6 | 2 | 0 | 6.29 | .380 | 1.83 | 11.6 | 5.0 | 7.1 | 34.1 | 44 | 25 | 24 | 3 | 19 | 27 | 0 | 0 | 0 | 0 | 2 | 0 | 4 | 4.24 |
| SP | Shields, J.Shields, James >> | 30 | 2011 | R | 62 | 6 | 6 | 1 | 4 | 6.23 | .374 | 1.79 | 12.2 | 3.9 | 6.0 | 39.0 | 53 | 34 | 27 | 2 | 17 | 26 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.64 |
| SP | Wainwright, A.Wainwright, Adam >> | 29 | 2010 | R | 55 | 6 | 5 | 3 | 3 | 4.17 | .353 | 1.64 | 10.5 | 4.5 | 6.8 | 36.2 | 42 | 19 | 17 | 5 | 18 | 27 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 4.81 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 14 | 0 | 0 | 0 | 2.60 | .224 | 0.87 | 6.9 | 1.1 | 11.1 | 17.1 | 13 | 5 | 5 | 2 | 2 | 21 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 2.41 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 81 | 19 | 0 | 0 | 1 | 2.28 | .245 | 0.93 | 4.7 | 3.9 | 12.5 | 23.2 | 12 | 8 | 6 | 0 | 10 | 32 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 1.65 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 10 | 0 | 0 | 2 | 3.97 | .333 | 1.41 | 8.2 | 4.9 | 8.2 | 11.1 | 10 | 5 | 5 | 1 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.27 |
| RP | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 66 | 10 | 0 | 2 | 1 | 1.50 | .294 | 1.25 | 9.0 | 2.3 | 11.3 | 12.0 | 12 | 2 | 2 | 1 | 3 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.33 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 58 | 10 | 0 | 0 | 0 | 0.90 | .231 | 0.90 | 6.3 | 1.8 | 11.7 | 10.0 | 7 | 2 | 1 | 0 | 2 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| SP | Castillo, L.Castillo, Luis >> | 26 | 2019 | R | 49 | 2 | 1 | 1 | 0 | 0.00 | .296 | 1.26 | 6.0 | 6.0 | 9.0 | 6.1 | 4 | 2 | 0 | 0 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |