| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 16 | 16 | 7 | 2 | 4.89 | .335 | 1.48 | 9.1 | 4.3 | 9.3 | 99.1 | 100 | 55 | 54 | 13 | 47 | 102 | 0 | 0 | 0 | 0 | 9 | 3 | 5 | 4.16 |
| SP | Carrasco, C.Carrasco, Carlos >> | 27 | 2014 | R | 84 | 16 | 16 | 0 | 6 | 3.59 | .311 | 1.34 | 9.5 | 2.7 | 9.6 | 57.2 | 60 | 26 | 23 | 9 | 17 | 61 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.86 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 75 | 16 | 16 | 5 | 4 | 4.47 | .305 | 1.32 | 8.6 | 3.3 | 8.4 | 98.2 | 94 | 51 | 49 | 15 | 36 | 92 | 0 | 0 | 0 | 0 | 10 | 0 | 2 | 4.21 |
| SP | Iwakuma, H.Iwakuma, Hisashi >> | 32 | 2013 | R | 65 | 17 | 16 | 7 | 8 | 4.64 | .328 | 1.38 | 9.8 | 2.8 | 5.8 | 108.2 | 117 | 57 | 56 | 16 | 33 | 69 | 3 | 0 | 0 | 0 | 6 | 9 | 7 | 4.81 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 48 | 0 | 4 | 7 | 4.54 | .295 | 1.24 | 9.3 | 2.0 | 10.7 | 69.1 | 71 | 38 | 35 | 12 | 15 | 82 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 3.58 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 87 | 49 | 0 | 3 | 0 | 4.67 | .322 | 1.39 | 8.6 | 4.1 | 10.8 | 61.2 | 58 | 32 | 32 | 11 | 28 | 73 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 4.43 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 75 | 44 | 0 | 2 | 4 | 3.99 | .315 | 1.35 | 8.4 | 3.9 | 11.8 | 58.2 | 54 | 26 | 26 | 7 | 25 | 76 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 3.34 |
| RP | Frieri, E.Frieri, Ernesto >> | 26 | 2012 | R | 68 | 40 | 0 | 3 | 4 | 6.28 | .374 | 1.77 | 9.4 | 6.5 | 7.7 | 43.0 | 45 | 30 | 30 | 12 | 31 | 37 | 0 | 3 | 4 | 0 | 0 | 1 | 0 | 7.14 |