| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 36 | 36 | 18 | 11 | 3.43 | .261 | 1.01 | 7.6 | 1.5 | 9.7 | 268.0 | 227 | 102 | 102 | 34 | 45 | 288 | 5 | 0 | 0 | 0 | 26 | 12 | 6 | 3.14 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 84 | 34 | 34 | 9 | 16 | 4.57 | .327 | 1.41 | 9.4 | 3.3 | 7.4 | 208.2 | 218 | 108 | 106 | 23 | 76 | 172 | 0 | 0 | 0 | 0 | 16 | 10 | 8 | 4.02 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 90 | 33 | 33 | 10 | 13 | 4.36 | .304 | 1.26 | 7.7 | 3.6 | 9.5 | 198.0 | 170 | 98 | 96 | 27 | 79 | 210 | 1 | 0 | 0 | 1 | 15 | 10 | 4 | 4.00 |
| SP | Severino, L.Severino, Luis >> | 23 | 2017 | R | 74 | 33 | 33 | 16 | 8 | 4.48 | .318 | 1.40 | 8.9 | 3.7 | 10.1 | 199.0 | 196 | 107 | 99 | 34 | 82 | 224 | 0 | 0 | 0 | 0 | 17 | 1 | 3 | 4.22 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 69 | 31 | 31 | 8 | 17 | 6.10 | .335 | 1.48 | 10.2 | 3.1 | 7.9 | 183.0 | 208 | 126 | 124 | 46 | 63 | 161 | 2 | 0 | 0 | 1 | 10 | 6 | 5 | 5.64 |
| CL | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 69 | 0 | 4 | 4 | 2.78 | .269 | 1.05 | 6.4 | 3.0 | 9.7 | 74.1 | 53 | 23 | 23 | 5 | 25 | 80 | 0 | 45 | 4 | 0 | 0 | 4 | 0 | 2.89 |
| SU | Miller, A.Miller, Andrew >> | 30 | 2015 | L | 85 | 72 | 0 | 3 | 2 | 2.96 | .275 | 1.11 | 6.5 | 3.5 | 9.6 | 79.0 | 57 | 27 | 26 | 9 | 31 | 84 | 0 | 1 | 5 | 0 | 0 | 2 | 2 | 3.61 |
| RP | Robertson, D.Robertson, David >> | 32 | 2017 | R | 86 | 88 | 0 | 4 | 1 | 3.42 | .289 | 1.21 | 6.8 | 4.1 | 10.4 | 76.1 | 57 | 29 | 29 | 9 | 35 | 88 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 3.64 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 89 | 0 | 4 | 3 | 4.04 | .300 | 1.27 | 6.4 | 5.0 | 9.9 | 49.0 | 35 | 22 | 22 | 5 | 27 | 54 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 3.84 |
| RP | Petit, Y.Petit, Yusmeiro >> | 35 | 2019 | R | 71 | 60 | 0 | 7 | 2 | 3.16 | .217 | 0.81 | 6.2 | 1.2 | 7.1 | 62.2 | 43 | 22 | 22 | 10 | 8 | 49 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.95 |
| RP | Feliz, N.Feliz, Neftali >> | 22 | 2010 | R | 66 | 33 | 0 | 1 | 1 | 2.80 | .254 | 0.99 | 5.1 | 3.9 | 11.3 | 35.1 | 20 | 11 | 11 | 2 | 15 | 44 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 2.60 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 52 | 32 | 0 | 1 | 1 | 2.81 | .262 | 1.00 | 7.3 | 1.7 | 9.0 | 32.0 | 26 | 10 | 10 | 5 | 6 | 32 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 3.78 |