| SP | Johnson, W.Johnson, Walter $ >> | 26 | 1913 | R | 95 | 32 | 32 | 14 | 13 | 3.29 | .262 | 1.05 | 7.7 | 1.8 | 5.5 | 229.2 | 195 | 95 | 84 | 24 | 46 | 140 | 8 | 0 | 0 | 1 | 22 | 3 | 7 | 3.78 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 31 | 31 | 11 | 12 | 4.11 | .317 | 1.38 | 8.5 | 3.9 | 5.9 | 195.0 | 184 | 97 | 89 | 20 | 85 | 127 | 1 | 0 | 0 | 0 | 17 | 3 | 2 | 4.38 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 31 | 31 | 11 | 15 | 3.89 | .298 | 1.26 | 8.5 | 2.8 | 6.4 | 227.0 | 214 | 106 | 98 | 24 | 71 | 161 | 12 | 0 | 0 | 2 | 19 | 4 | 9 | 3.95 |
| CL | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 53 | 0 | 2 | 2 | 2.40 | .272 | 1.12 | 6.1 | 4.0 | 7.9 | 56.1 | 38 | 16 | 15 | 5 | 25 | 49 | 0 | 36 | 4 | 0 | 0 | 0 | 1 | 3.75 |
| SU | Hader, J.Hader, Josh $$ >> | 24 | 2018 | L | 93 | 53 | 0 | 2 | 4 | 2.91 | .237 | 0.90 | 4.7 | 3.4 | 10.6 | 55.2 | 29 | 20 | 18 | 5 | 21 | 65 | 0 | 3 | 5 | 0 | 0 | 2 | 0 | 3.07 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 48 | 0 | 3 | 4 | 4.56 | .299 | 1.24 | 8.4 | 2.8 | 7.0 | 49.1 | 46 | 29 | 25 | 8 | 15 | 38 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.61 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 31 | 0 | 2 | 1 | 4.04 | .344 | 1.57 | 7.7 | 6.7 | 7.7 | 35.2 | 30 | 17 | 16 | 1 | 26 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.89 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 26 | 0 | 2 | 0 | 5.33 | .361 | 1.70 | 12.6 | 2.9 | 9.4 | 25.1 | 35 | 16 | 15 | 4 | 8 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.96 |