| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 25 | 25 | 5 | 14 | 5.13 | .326 | 1.44 | 8.5 | 4.5 | 8.7 | 149.0 | 140 | 97 | 85 | 25 | 74 | 144 | 1 | 0 | 0 | 0 | 12 | 2 | 4 | 4.78 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 24 | 24 | 9 | 6 | 5.92 | .337 | 1.53 | 10.5 | 3.3 | 4.7 | 132.1 | 154 | 91 | 87 | 18 | 48 | 69 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 4.82 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 23 | 23 | 9 | 8 | 4.94 | .330 | 1.45 | 9.5 | 3.6 | 4.4 | 136.2 | 143 | 83 | 75 | 21 | 55 | 66 | 0 | 0 | 0 | 0 | 10 | 4 | 2 | 5.34 |
| SP | Drysdale, D.Drysdale, Don # >> | 28 | 1964 | R | 58 | 23 | 23 | 12 | 6 | 4.25 | .307 | 1.30 | 9.0 | 2.8 | 4.9 | 171.2 | 171 | 91 | 81 | 17 | 53 | 93 | 8 | 0 | 0 | 1 | 12 | 4 | 3 | 4.20 |
| RP | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 69 | 0 | 7 | 5 | 4.22 | .267 | 1.06 | 7.6 | 1.9 | 7.1 | 98.0 | 83 | 49 | 46 | 11 | 21 | 77 | 0 | 11 | 2 | 0 | 0 | 3 | 3 | 3.62 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 74 | 55 | 0 | 3 | 0 | 3.70 | .304 | 1.28 | 7.5 | 4.2 | 7.5 | 65.2 | 54 | 31 | 27 | 9 | 30 | 54 | 0 | 10 | 2 | 0 | 0 | 2 | 3 | 4.62 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 44 | 39 | 0 | 4 | 3 | 4.47 | .322 | 1.42 | 7.8 | 5.1 | 8.6 | 46.1 | 40 | 24 | 23 | 6 | 26 | 44 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.48 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 15 | 0 | 1 | 0 | 1.77 | .228 | 0.89 | 6.8 | 1.4 | 5.4 | 20.1 | 15 | 4 | 4 | 2 | 3 | 12 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 3.55 |