| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 32 | 32 | 9 | 16 | 3.29 | .267 | 1.07 | 6.7 | 2.9 | 8.0 | 227.0 | 169 | 90 | 83 | 32 | 73 | 201 | 4 | 0 | 0 | 1 | 21 | 6 | 3 | 4.11 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 85 | 30 | 30 | 5 | 17 | 6.24 | .337 | 1.50 | 10.2 | 3.3 | 8.1 | 181.2 | 206 | 131 | 126 | 31 | 67 | 162 | 2 | 0 | 0 | 0 | 8 | 4 | 1 | 4.61 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 30 | 30 | 11 | 13 | 4.89 | .310 | 1.33 | 9.3 | 2.7 | 7.3 | 213.1 | 220 | 125 | 116 | 27 | 63 | 173 | 4 | 0 | 0 | 1 | 12 | 5 | 7 | 3.98 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 30 | 30 | 12 | 15 | 5.79 | .345 | 1.55 | 10.4 | 3.5 | 6.1 | 194.1 | 225 | 138 | 125 | 30 | 76 | 131 | 6 | 0 | 0 | 1 | 9 | 6 | 9 | 4.93 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 80 | 0 | 2 | 4 | 3.06 | .291 | 1.22 | 6.3 | 4.8 | 8.3 | 108.2 | 76 | 41 | 37 | 9 | 57 | 99 | 0 | 5 | 1 | 0 | 0 | 1 | 4 | 3.86 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 81 | 0 | 8 | 2 | 3.34 | .288 | 1.19 | 5.7 | 5.0 | 10.0 | 91.2 | 58 | 35 | 34 | 7 | 51 | 101 | 0 | 7 | 4 | 0 | 0 | 2 | 7 | 3.53 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 54 | 0 | 4 | 0 | 3.41 | .345 | 1.57 | 8.7 | 5.6 | 9.6 | 60.2 | 58 | 25 | 23 | 7 | 37 | 64 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 4.28 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 45 | 0 | 4 | 2 | 3.10 | .293 | 1.24 | 8.0 | 3.3 | 7.8 | 52.1 | 46 | 21 | 18 | 8 | 19 | 45 | 0 | 4 | 1 | 0 | 0 | 0 | 3 | 4.37 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 54 | 2 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 6.0 | 3.0 | 3.0 | 3.0 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.33 |