| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 25 | 25 | 8 | 6 | 4.35 | .286 | 1.19 | 8.5 | 2.2 | 9.1 | 155.0 | 146 | 81 | 75 | 23 | 38 | 157 | 2 | 0 | 0 | 0 | 12 | 2 | 1 | 3.68 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 24 | 24 | 11 | 8 | 4.35 | .288 | 1.20 | 8.6 | 2.2 | 9.6 | 153.0 | 146 | 77 | 74 | 16 | 37 | 163 | 2 | 0 | 0 | 2 | 14 | 3 | 1 | 3.01 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 26 | 24 | 9 | 11 | 6.96 | .363 | 1.66 | 11.0 | 4.0 | 7.1 | 130.2 | 159 | 104 | 101 | 27 | 58 | 103 | 2 | 0 | 0 | 1 | 6 | 6 | 2 | 5.59 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 24 | 24 | 4 | 13 | 6.13 | .334 | 1.46 | 11.2 | 2.1 | 8.8 | 127.2 | 158 | 94 | 87 | 23 | 29 | 124 | 1 | 0 | 0 | 0 | 8 | 5 | 1 | 4.20 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 65 | 0 | 4 | 4 | 3.80 | .315 | 1.37 | 8.2 | 4.1 | 10.1 | 71.0 | 65 | 31 | 30 | 5 | 32 | 80 | 0 | 24 | 7 | 0 | 0 | 1 | 1 | 3.06 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 67 | 0 | 2 | 3 | 4.92 | .312 | 1.29 | 7.6 | 4.1 | 9.1 | 75.0 | 63 | 45 | 41 | 8 | 34 | 76 | 0 | 2 | 2 | 0 | 0 | 5 | 0 | 3.92 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 68 | 0 | 2 | 2 | 3.91 | .351 | 1.61 | 9.7 | 4.8 | 9.3 | 78.1 | 84 | 36 | 34 | 2 | 42 | 81 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 2.91 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 62 | 0 | 3 | 1 | 2.89 | .328 | 1.47 | 8.4 | 4.9 | 10.0 | 71.2 | 66 | 24 | 23 | 4 | 39 | 79 | 0 | 1 | 4 | 0 | 0 | 0 | 1 | 3.15 |