| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 32 | 32 | 11 | 8 | 4.48 | .291 | 1.19 | 8.3 | 2.4 | 8.1 | 201.0 | 186 | 104 | 100 | 26 | 54 | 180 | 4 | 0 | 0 | 0 | 17 | 8 | 1 | 3.82 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 31 | 31 | 6 | 16 | 6.31 | .339 | 1.52 | 10.9 | 2.8 | 8.3 | 175.1 | 212 | 126 | 123 | 33 | 55 | 162 | 1 | 0 | 0 | 0 | 9 | 3 | 3 | 4.59 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 31 | 31 | 5 | 11 | 6.97 | .374 | 1.78 | 12.6 | 3.5 | 7.8 | 146.0 | 204 | 122 | 113 | 27 | 56 | 127 | 0 | 0 | 0 | 0 | 9 | 2 | 6 | 4.86 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 34 | 30 | 10 | 9 | 5.93 | .329 | 1.46 | 10.0 | 3.1 | 8.0 | 173.0 | 193 | 120 | 114 | 32 | 59 | 153 | 3 | 0 | 0 | 1 | 10 | 3 | 5 | 4.71 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 82 | 0 | 10 | 6 | 3.67 | .283 | 1.16 | 7.2 | 3.3 | 8.8 | 100.2 | 80 | 46 | 41 | 12 | 37 | 98 | 0 | 27 | 5 | 0 | 0 | 2 | 2 | 3.77 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 89 | 0 | 3 | 2 | 3.41 | .278 | 1.13 | 6.6 | 3.5 | 8.8 | 111.0 | 82 | 46 | 42 | 15 | 43 | 109 | 0 | 6 | 6 | 0 | 0 | 3 | 0 | 4.04 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 96 | 0 | 9 | 7 | 4.50 | .327 | 1.43 | 8.1 | 4.7 | 9.7 | 110.0 | 99 | 58 | 55 | 14 | 58 | 119 | 0 | 2 | 1 | 0 | 0 | 3 | 6 | 4.15 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 74 | 0 | 6 | 1 | 4.73 | .319 | 1.39 | 8.8 | 3.7 | 6.7 | 97.0 | 95 | 53 | 51 | 15 | 40 | 72 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.79 |