| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 32 | 32 | 19 | 9 | 3.61 | .308 | 1.28 | 7.4 | 4.2 | 7.0 | 202.0 | 165 | 87 | 81 | 15 | 94 | 157 | 2 | 0 | 0 | 1 | 19 | 11 | 2 | 3.97 |
| SP | Mathewson, C.Mathewson, Christy † >> | 29 | 1909 | R | 86 | 31 | 31 | 16 | 8 | 2.97 | .263 | 1.07 | 7.6 | 2.0 | 4.7 | 209.1 | 177 | 73 | 69 | 13 | 47 | 108 | 2 | 0 | 0 | 1 | 24 | 0 | 6 | 3.45 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 83 | 30 | 30 | 12 | 8 | 4.18 | .302 | 1.27 | 8.5 | 3.0 | 8.3 | 180.2 | 170 | 91 | 84 | 23 | 59 | 166 | 2 | 0 | 0 | 0 | 15 | 5 | 1 | 3.88 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 41 | 28 | 28 | 13 | 10 | 4.86 | .339 | 1.50 | 9.1 | 4.4 | 7.6 | 155.2 | 157 | 89 | 84 | 20 | 76 | 131 | 1 | 0 | 0 | 0 | 11 | 6 | 6 | 4.57 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 80 | 0 | 2 | 3 | 3.04 | .269 | 1.09 | 5.7 | 4.1 | 9.3 | 109.2 | 69 | 37 | 37 | 7 | 50 | 113 | 0 | 10 | 3 | 0 | 0 | 2 | 8 | 3.19 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 81 | 0 | 2 | 1 | 2.95 | .230 | 0.89 | 6.5 | 1.6 | 6.6 | 100.2 | 72 | 33 | 33 | 12 | 18 | 73 | 0 | 12 | 2 | 0 | 0 | 0 | 0 | 3.64 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 55 | 0 | 7 | 2 | 3.41 | .295 | 1.24 | 6.6 | 4.7 | 8.3 | 60.2 | 44 | 23 | 23 | 7 | 31 | 55 | 0 | 5 | 2 | 0 | 0 | 1 | 5 | 4.28 |