| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 32 | 32 | 17 | 7 | 2.93 | .244 | 0.94 | 6.4 | 2.1 | 8.2 | 218.0 | 156 | 74 | 71 | 24 | 50 | 199 | 5 | 0 | 0 | 2 | 22 | 5 | 0 | 3.36 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 31 | 31 | 16 | 8 | 3.45 | .280 | 1.16 | 7.8 | 2.6 | 5.7 | 226.2 | 197 | 88 | 87 | 25 | 65 | 142 | 13 | 0 | 0 | 2 | 19 | 2 | 1 | 4.07 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 80 | 30 | 30 | 13 | 7 | 4.96 | .309 | 1.33 | 8.8 | 3.2 | 4.3 | 185.0 | 181 | 108 | 102 | 24 | 65 | 89 | 5 | 0 | 0 | 2 | 11 | 2 | 3 | 4.81 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 31 | 29 | 12 | 12 | 5.32 | .320 | 1.40 | 8.9 | 3.8 | 6.5 | 162.1 | 160 | 103 | 96 | 26 | 68 | 117 | 2 | 0 | 0 | 2 | 12 | 1 | 1 | 4.92 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 78 | 0 | 5 | 4 | 2.45 | .243 | 0.92 | 6.2 | 2.1 | 9.5 | 110.1 | 76 | 31 | 30 | 6 | 26 | 116 | 0 | 8 | 1 | 0 | 0 | 4 | 3 | 2.42 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 69 | 0 | 8 | 3 | 3.08 | .249 | 0.97 | 6.1 | 2.6 | 7.7 | 96.1 | 65 | 33 | 33 | 5 | 28 | 82 | 0 | 12 | 2 | 0 | 0 | 3 | 1 | 2.94 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 42 | 0 | 5 | 1 | 4.83 | .313 | 1.32 | 7.7 | 4.2 | 9.4 | 41.0 | 35 | 22 | 22 | 9 | 19 | 43 | 0 | 5 | 0 | 0 | 0 | 2 | 2 | 5.29 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 31 | 0 | 2 | 0 | 1.24 | .227 | 0.85 | 5.5 | 2.3 | 10.3 | 36.1 | 22 | 5 | 5 | 0 | 9 | 41 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 1.56 |