| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 34 | 34 | 11 | 12 | 3.50 | .278 | 1.15 | 8.7 | 1.7 | 8.2 | 226.0 | 218 | 93 | 88 | 28 | 42 | 205 | 0 | 0 | 0 | 0 | 24 | 1 | 3 | 3.37 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 35 | 35 | 16 | 12 | 3.72 | .307 | 1.31 | 8.8 | 3.0 | 5.5 | 249.0 | 243 | 112 | 103 | 25 | 84 | 152 | 3 | 0 | 0 | 0 | 23 | 4 | 5 | 4.14 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 32 | 32 | 14 | 7 | 3.50 | .299 | 1.25 | 7.7 | 3.6 | 5.7 | 211.0 | 180 | 89 | 82 | 23 | 84 | 133 | 0 | 0 | 0 | 0 | 22 | 6 | 3 | 4.44 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 24 | 24 | 14 | 7 | 3.41 | .288 | 1.19 | 7.7 | 3.0 | 5.1 | 184.2 | 157 | 81 | 70 | 12 | 62 | 104 | 11 | 0 | 0 | 2 | 14 | 5 | 5 | 3.81 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 75 | 0 | 4 | 4 | 2.60 | .309 | 1.31 | 6.2 | 5.7 | 9.7 | 65.2 | 45 | 23 | 19 | 5 | 41 | 70 | 0 | 26 | 3 | 0 | 0 | 2 | 2 | 3.83 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 87 | 0 | 4 | 0 | 3.82 | .236 | 0.91 | 6.3 | 1.9 | 7.6 | 66.0 | 46 | 30 | 28 | 10 | 14 | 56 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.95 |
| RP | Rivera, M.Rivera, Mariano # >> | 39 | 2008 | R | 85 | 54 | 0 | 5 | 5 | 5.18 | .282 | 1.18 | 9.4 | 1.3 | 8.1 | 41.2 | 43 | 25 | 24 | 6 | 6 | 37 | 0 | 8 | 3 | 0 | 0 | 0 | 1 | 3.54 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 41 | 0 | 5 | 4 | 3.89 | .311 | 1.36 | 8.2 | 4.2 | 9.8 | 34.2 | 31 | 16 | 15 | 4 | 16 | 37 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 32 | 0 | 0 | 5 | 3.86 | .247 | 0.99 | 6.7 | 2.3 | 9.8 | 23.1 | 17 | 10 | 10 | 5 | 6 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.43 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 32 | 32 | 11 | 10 | 4.02 | .290 | 1.21 | 8.7 | 2.2 | 4.4 | 233.0 | 226 | 114 | 104 | 23 | 56 | 113 | 5 | 0 | 0 | 1 | 18 | 4 | 7 | 4.09 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 41 | 20 | 3 | 5 | 2 | 5.03 | .330 | 1.46 | 8.2 | 4.9 | 7.8 | 59.0 | 54 | 33 | 33 | 11 | 32 | 51 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 5.37 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 43 | 0 | 0 | 0 | 2.13 | .392 | 1.93 | 11.5 | 6.1 | 9.4 | 25.1 | 32 | 8 | 6 | 2 | 17 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.00 |