| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 34 | 34 | 7 | 11 | 3.85 | .309 | 1.32 | 7.8 | 4.1 | 8.2 | 224.1 | 195 | 107 | 96 | 24 | 101 | 203 | 4 | 0 | 0 | 2 | 20 | 5 | 3 | 4.00 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 33 | 33 | 12 | 17 | 4.68 | .317 | 1.38 | 9.3 | 3.1 | 5.0 | 219.1 | 227 | 121 | 114 | 32 | 75 | 122 | 9 | 0 | 0 | 2 | 18 | 4 | 4 | 4.87 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 32 | 32 | 11 | 16 | 5.93 | .330 | 1.45 | 9.3 | 3.8 | 5.1 | 198.2 | 205 | 136 | 131 | 33 | 84 | 113 | 5 | 0 | 0 | 0 | 12 | 5 | 2 | 5.37 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 94 | 85 | 0 | 5 | 4 | 2.69 | .282 | 1.15 | 7.0 | 3.4 | 9.4 | 117.0 | 91 | 38 | 35 | 10 | 44 | 122 | 0 | 10 | 4 | 0 | 0 | 3 | 0 | 3.23 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 62 | 0 | 3 | 5 | 4.30 | .298 | 1.24 | 8.4 | 2.8 | 9.3 | 81.2 | 76 | 41 | 39 | 12 | 25 | 84 | 0 | 5 | 0 | 0 | 0 | 3 | 0 | 3.89 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 47 | 0 | 4 | 5 | 3.98 | .309 | 1.29 | 7.4 | 4.2 | 5.8 | 81.1 | 67 | 37 | 36 | 11 | 38 | 52 | 0 | 3 | 4 | 0 | 0 | 4 | 2 | 5.04 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 42 | 0 | 2 | 0 | 3.71 | .295 | 1.25 | 7.4 | 3.9 | 5.5 | 51.0 | 42 | 21 | 21 | 6 | 22 | 31 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.61 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 2 | 1 | 0 | 1 | 24.75 | .571 | 4.00 | 31.5 | 4.5 | 4.5 | 4.0 | 14 | 11 | 11 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.75 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 20 | 0 | 3 | 0 | 5.44 | .332 | 1.49 | 10.7 | 2.7 | 9.8 | 43.0 | 51 | 26 | 26 | 10 | 13 | 47 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.74 |