| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 30 | 30 | 11 | 11 | 3.70 | .294 | 1.24 | 7.5 | 3.6 | 8.2 | 231.0 | 193 | 100 | 95 | 23 | 93 | 211 | 8 | 0 | 0 | 0 | 18 | 2 | 8 | 3.70 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 29 | 29 | 11 | 13 | 3.76 | .294 | 1.23 | 8.7 | 2.4 | 5.4 | 215.2 | 208 | 93 | 90 | 20 | 57 | 130 | 7 | 0 | 0 | 2 | 18 | 4 | 2 | 3.85 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 29 | 29 | 5 | 14 | 5.11 | .323 | 1.42 | 9.4 | 3.4 | 5.2 | 185.0 | 193 | 108 | 105 | 28 | 70 | 106 | 7 | 0 | 0 | 3 | 11 | 2 | 6 | 4.99 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 29 | 29 | 2 | 5 | 4.80 | .315 | 1.34 | 8.8 | 3.3 | 9.9 | 122.0 | 119 | 69 | 65 | 17 | 45 | 134 | 0 | 0 | 0 | 0 | 1 | 4 | 3 | 3.82 |
| SP | Schilling, C.Schilling, Curt # >> | 36 | 2002 | R | 50 | 28 | 28 | 7 | 16 | 5.09 | .325 | 1.43 | 10.3 | 2.6 | 8.3 | 189.1 | 216 | 111 | 107 | 30 | 54 | 174 | 5 | 0 | 0 | 0 | 14 | 3 | 4 | 4.13 |
| RP | Feliz, N.Feliz, Neftali # >> | 21 | 2009 | R | 97 | 72 | 0 | 11 | 7 | 4.46 | .309 | 1.31 | 8.2 | 3.6 | 8.9 | 117.0 | 106 | 61 | 58 | 13 | 47 | 116 | 0 | 3 | 4 | 0 | 0 | 4 | 0 | 3.77 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 62 | 0 | 5 | 2 | 3.09 | .308 | 1.31 | 7.3 | 4.6 | 9.5 | 78.2 | 63 | 29 | 27 | 6 | 40 | 82 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 3.51 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 53 | 0 | 6 | 3 | 2.74 | .298 | 1.28 | 8.0 | 3.5 | 9.4 | 69.0 | 61 | 23 | 21 | 6 | 27 | 72 | 0 | 3 | 1 | 0 | 0 | 0 | 4 | 3.22 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 41 | 0 | 7 | 7 | 4.17 | .343 | 1.54 | 7.8 | 6.0 | 6.8 | 69.0 | 60 | 34 | 32 | 8 | 46 | 52 | 0 | 7 | 4 | 0 | 0 | 2 | 2 | 5.09 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 26 | 0 | 1 | 1 | 4.85 | .355 | 1.62 | 11.4 | 3.1 | 4.5 | 26.0 | 33 | 14 | 14 | 2 | 9 | 13 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.15 |