| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 30 | 30 | 10 | 13 | 4.86 | .317 | 1.37 | 9.4 | 3.0 | 5.1 | 209.1 | 218 | 117 | 113 | 20 | 69 | 118 | 3 | 0 | 0 | 0 | 15 | 4 | 6 | 4.16 |
| SP | Arrieta, J.Arrieta, Jake † # >> | 29 | 2015 | R | 93 | 29 | 29 | 17 | 9 | 3.64 | .292 | 1.22 | 8.0 | 3.0 | 7.4 | 207.2 | 185 | 94 | 84 | 16 | 68 | 170 | 5 | 0 | 0 | 1 | 18 | 4 | 7 | 3.41 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 29 | 29 | 12 | 12 | 4.74 | .309 | 1.33 | 9.0 | 2.9 | 5.7 | 209.0 | 210 | 116 | 110 | 20 | 68 | 133 | 10 | 0 | 0 | 2 | 13 | 3 | 6 | 3.99 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 28 | 28 | 12 | 10 | 4.99 | .342 | 1.53 | 8.7 | 5.1 | 4.8 | 182.1 | 175 | 105 | 101 | 18 | 104 | 97 | 4 | 0 | 0 | 1 | 11 | 5 | 3 | 5.02 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 69 | 0 | 2 | 5 | 2.40 | .299 | 1.27 | 7.3 | 4.1 | 9.5 | 75.0 | 61 | 22 | 20 | 6 | 34 | 79 | 0 | 10 | 5 | 0 | 0 | 1 | 0 | 3.33 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 46 | 0 | 4 | 1 | 3.86 | .325 | 1.44 | 7.9 | 5.1 | 10.1 | 51.1 | 45 | 22 | 22 | 7 | 29 | 57 | 0 | 8 | 1 | 0 | 0 | 0 | 3 | 4.25 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 29 | 0 | 2 | 3 | 4.55 | .360 | 1.65 | 10.2 | 5.0 | 9.9 | 29.2 | 33 | 17 | 15 | 2 | 16 | 32 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 3.45 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 18 | 0 | 1 | 0 | 3.15 | .294 | 1.25 | 8.1 | 3.2 | 5.4 | 20.0 | 18 | 8 | 7 | 4 | 7 | 12 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 5.45 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 17 | 0 | 1 | 1 | 3.60 | .338 | 1.47 | 8.4 | 4.8 | 8.4 | 15.0 | 14 | 6 | 6 | 1 | 8 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.80 |