| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 4 | 4 | 2 | 2 | 2.10 | .294 | 1.17 | 8.6 | 2.2 | 10.8 | 25.2 | 24 | 6 | 6 | 2 | 6 | 30 | 0 | 0 | 0 | 0 | 3 | 2 | 1 | 2.60 |
| SP | Schwellenbach, S.Schwellenbach, Spencer >> | 25 | 2025 | R | 87 | 4 | 4 | 1 | 2 | 2.89 | .282 | 1.14 | 8.7 | 1.6 | 7.1 | 28.0 | 27 | 12 | 9 | 2 | 5 | 22 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 3.00 |
| SP | Gausman, K.Gausman, Kevin >> | 34 | 2025 | R | 84 | 4 | 4 | 1 | 3 | 4.74 | .282 | 1.14 | 8.6 | 1.9 | 10.5 | 24.2 | 23 | 13 | 13 | 4 | 5 | 28 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 3.58 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 82 | 4 | 4 | 0 | 3 | 6.55 | .389 | 1.91 | 13.5 | 3.7 | 11.0 | 22.0 | 33 | 17 | 16 | 3 | 9 | 27 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 3.55 |
| RP | Kittredge, A.Kittredge, Andrew >> | 35 | 2025 | R | 84 | 11 | 0 | 0 | 0 | 5.52 | .333 | 1.50 | 10.3 | 3.9 | 11.6 | 14.2 | 16 | 9 | 9 | 2 | 6 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.57 |
| RP | Bautista, F.Bautista, Félix >> | 30 | 2025 | R | 83 | 11 | 0 | 0 | 1 | 3.95 | .255 | 0.95 | 3.5 | 5.5 | 11.8 | 13.2 | 5 | 6 | 6 | 1 | 8 | 17 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.46 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 78 | 7 | 0 | 0 | 0 | 5.63 | .294 | 1.25 | 9.0 | 2.3 | 7.9 | 8.0 | 8 | 5 | 5 | 1 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.63 |
| RP | Whitlock, G.Whitlock, Garrett >> | 29 | 2025 | R | 73 | 6 | 0 | 0 | 0 | 2.57 | .323 | 1.29 | 10.3 | 1.3 | 10.3 | 7.0 | 8 | 2 | 2 | 1 | 1 | 8 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.43 |
| RP | Flexen, C.Flexen, Christopher >> | 30 | 2025 | R | 45 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |