| SP | Skubal, T.Skubal, Tarik $ >> | 28 | 2025 | L | 100 | 21 | 21 | 6 | 9 | 2.95 | .297 | 1.23 | 8.1 | 3.0 | 10.6 | 134.1 | 121 | 54 | 44 | 12 | 44 | 158 | 0 | 0 | 0 | 0 | 14 | 5 | 3 | 2.90 |
| SP | Skenes, P.Skenes, Paul $$ >> | 23 | 2025 | R | 95 | 21 | 21 | 8 | 9 | 3.88 | .292 | 1.22 | 8.2 | 2.8 | 10.6 | 130.0 | 118 | 62 | 56 | 14 | 40 | 153 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 3.04 |
| SP | Crochet, G.Crochet, Garrett $ >> | 26 | 2025 | L | 89 | 20 | 20 | 9 | 9 | 4.25 | .300 | 1.26 | 9.1 | 2.3 | 9.9 | 131.1 | 132 | 73 | 62 | 21 | 34 | 144 | 1 | 0 | 0 | 1 | 11 | 3 | 0 | 3.73 |
| SP | Luzardo, J.Luzardo, Jesus >> | 27 | 2025 | L | 68 | 20 | 20 | 7 | 8 | 4.81 | .342 | 1.53 | 10.8 | 3.0 | 10.6 | 112.1 | 135 | 68 | 60 | 20 | 37 | 132 | 0 | 0 | 0 | 0 | 9 | 3 | 1 | 4.04 |
| SP | Valdez, F.Valdez, Framber >> | 31 | 2025 | L | 61 | 21 | 20 | 4 | 8 | 6.16 | .368 | 1.71 | 10.9 | 4.5 | 8.8 | 114.0 | 138 | 86 | 78 | 18 | 57 | 112 | 0 | 0 | 0 | 0 | 5 | 4 | 7 | 4.69 |
| CL | Jansen, K.Jansen, Kenley >> | 37 | 2025 | R | 88 | 52 | 0 | 2 | 6 | 3.38 | .307 | 1.28 | 7.3 | 4.2 | 9.2 | 53.1 | 43 | 26 | 20 | 3 | 25 | 54 | 0 | 23 | 1 | 0 | 0 | 3 | 0 | 3.28 |
| RP | Herget, J.Herget, Jimmy >> | 31 | 2025 | R | 54 | 50 | 0 | 2 | 1 | 6.43 | .380 | 1.76 | 10.1 | 5.7 | 9.4 | 63.0 | 71 | 49 | 45 | 8 | 40 | 66 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 4.70 |